Soluble urokinase plasminogen activator receptor (suPAR) is intensively studied as a biomarker of inflammation and disease outcome in various diseases. In rheumatoid arthritis (RA), suPAR have shown an association with swollen joints, but data on relation to early course progression are lacking. This study investigates the potential predict or reflect RA. Serum was measured by enzyme-linked imm...

A reliable and valid neurophysiological index of error-monitoring ability is an eventrelated potential (ERP) known as “error-related negativity” (ERN), which is evoked following an error response. Individuals with schizophrenia show error monitoring deficits accompanied by reduced ERN. Error monitoring is mediated in part by the medial-frontal cortex, which has been shown to be abnormal in schi...

Schizotypal personality is characterized by a variety of traits, such as magical thinking, unusual perceptual experiences, and anhedonia. Factor analytic studies have shown that these characteristics tend to cluster into at least two separate dimensions (positive and negative schizotypy). Schizotypy is associated with vulnerability to schizophrenia. However, it is also related to higher scores ...

Subserved by a dense network of neuroanatomical connections within the cerebrum, the cerebellum fulfills a crucial role in various motor, cognitive, and affective functions, and is located immediately below the skull. As a result, the cerebellum appears an interesting target for modern noninvasive stimulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct cur...

This chapter is framed by four perspectives. The fi rst views schizophrenia as a heterogeneous disorder that may present itself very differently across individuals. Heterogeneity has important implications for treatment approaches: for treatments to be optimally effective, they need to be tailored to the individual. The second perspective integrates what are often considered separate and diverg...

availablehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=11952520&dopt;=Abstract 22 Maidment R., Livingston G., Katona C. (2002). "Just keep taking thetablets": Adherence to antidepressant treatment in older people in primary care.International Journal of Geriatric Psychiatry, 17 (8), 752-757. This paper reports on the prevalence and factors affecti...

The indications for impacted third molar extraction include the prevention of dental reabsorption on the adjacent tooth. Resorption can be classifi ed as physiological (when deciduous teeth are exfoliated) or pathological (when caused by injury or irritation to the periodontal ligament). Many causes can trigger external root resorption (ERR), the most common cause of which is orthodontic forces...

-Adrenergic receptor blockers decrease intravenous anesthetic dose requirements. The present study determined the effect of propranolol on indocyanine green and antipyrine disposition from the moment of rapid intravenous injection. Antipyrine is a physiological marker that distributes to a volume as large as total body water in a blood flow-dependent manner and is a pharmacokinetic surrogate fo...

As an approach to treatment of psychosis, Open Dialogue aims to begin treatment within 24 hours of first contact between the health system and the patient or family, and in accordance with social constructionist principles, includes the family and the social network in open discussion of all issues throughout treatment. As one step toward evaluating the impact of this novel model of care, stati...

24 We compared the preclinical safety and efficacy of Tenofovir (TFV) 1% gel and 25 MZC gel containing 50 μM MIV-150 (M), 14 mM Zn(O2CCH3)2(H2O)2 (Z) and 3% 26 carrageenan (C) through a series of in vitro, ex vivo and in vivo assays. Both gels 27 showed good antiviral therapeutic indexes (>25-800). MZC showed greater anti28 SHIV-RT activity than TFV 1% gel in rhesus macaque vaginal explants. MZ...