نتایج جستجو برای: and ngs r 0950 p

تعداد نتایج: 17047258  

2017
Kei Omata Sharath K. Anand Daniel H. Hovelson Chia-Jen Liu Yuto Yamazaki Yasuhiro Nakamura Sadayoshi Ito Fumitoshi Satoh Hironobu Sasano William E. Rainey Scott A. Tomlins

Context Aldosterone synthase (CYP11B2) immunohistochemistry and next-generation sequencing (NGS) have revealed the frequent presence of aldosterone-producing cell clusters (APCCs) harboring somatic mutations in aldosterone-regulating genes in adrenals from Americans without defined hypertension status. Objective Determine the frequency and somatic mutation status of APCCs in a Japanese nonhyp...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2016
Sydney Dubois Pierre-Julien Viailly Sylvain Mareschal Elodie Bohers Philippe Bertrand Philippe Ruminy Catherine Maingonnat Jean-Philippe Jais Pauline Peyrouze Martin Figeac Thierry J Molina Fabienne Desmots Thierry Fest Corinne Haioun Thierry Lamy Christiane Copie-Bergman Josette Brière Tony Petrella Danielle Canioni Bettina Fabiani Bertrand Coiffier Richard Delarue Frédéric Peyrade André Bosly Marc André Nicolas Ketterer Gilles Salles Hervé Tilly Karen Leroy Fabrice Jardin

PURPOSE Next-generation sequencing (NGS) has detailed the genomic characterization of diffuse large B-cell lymphoma (DLBCL) by identifying recurrent somatic mutations. We set out to design a clinically feasible NGS panel focusing on genes whose mutations hold potential therapeutic impact. Furthermore, for the first time, we evaluated the prognostic value of these mutations in prospective clinic...

Journal: :iranian biomedical journal 0
mohammad reza alaei saeed talebi mohammad ghofrani mohsen taghizadeh mohammad keramatipour

background: progressive encephalopathy with or without lipodystrophy is a rare autosomal recessive childhood-onset seipin-associated neurodegenerative syndrome, leading to developmental regression of motor and cognitive skills. in this study, we introduce a patient with developmental regression and autism. the causative mutation was found by exome sequencing. methods: the proband showed a gener...

2010
R. L. SAN SOUCIE

for all w, x, y and showed by example that (1.1) can fail to hold. Prior to this, Kleinfeld [l ] generalized the Skornyakov theorem in another direction by assuming only the absence of one sort of nilpotent element. We now specify Kleinfeld's result in detail. Let F be the free nonassociative ring generated by Xi and x2 and suppose that R is any right alternative ring. Kleinfeld calls t, u, v i...

Journal: :Scientific American 1911

Journal: :Journal of Multivariate Analysis 1988

Journal: :Sri Lanka Journal of Surgery 2011

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