We here describe a new palladium-catalyzed oxidative 6-exo-trig cyclization of 1,6-enynes at room temperature using tBuONO as an oxidant for the synthesis of 3-bicyclo[4.1.0]heptan-5-ones. This cascade strategy involves the hydration, cyclization and cyclopropanation sequence, and represents a new transition-metal-catalyzed oxidative cyclization of 1,6-enynes in a 6-exo-trig fashion.

A procedure for the isolation of exo-beta-N-acetylglucosaminidase mutants, by using a plate assay method incorporating a fluorescent substrate, has been developed. A mutant lacking exo-beta-N-acetylglucosaminidase activity has been isolated and shown to grow, divide, autolyze, and sporulate as well as the parental strain.

The thermal stability of Newcastle disease virus has been characterized in terms of the rate constants for inactivation of hemagglutinating activity (HA), neuraminidase activity (NA), and infectivity. Inactivation of HA results in the concomitant loss of NA. Infectivity, however, is much more thermolabile. Disintegration of the virus particle is not responsible for the identical rate constants ...

We present a Chandra observation of the globular cluster Terzan 5 during times when the neutron-star X-ray transient EXO 1745–248 located in this cluster was in its quiescent state. We detected the quiescent system with a (0.5–10 keV) luminosity of ∼ 2 × 10 ergs s. This is similar to several other neutronstar transients observed in their quiescent states. However, the quiescent Xray spectrum of...

Breast cancer (BC) is the first in terms of frequency and mortality women. The aim this retrospective study to identify role exosome microRNAs (Exo-miRNAs) as possible early biomarkers for identifying patients with higher risk developing disease personalize their screening programmes. For purpose, Exo-miRNAs derived from cyst fluid women affected by Gross Cyst Disease (GCDB - a benign mammary g...

Phenomenon Hallyu that has become endemic in several countries does offer its own entertainment. Talking about K-Pop, it's always an interesting thing to discuss considering significant development. The love of fans for their idols makes whatever the latest news is spread on social media will be monitored at any time regardless time. .This study aims find out how behavior patterns boyband EXO, ...

Recently, a nitrogen iceberg was proposed as possible origin for the first interstellar object, 1I/2017 U1, also known ‘Oumuamua. Here, we show that mass budget in exo-Pluto planets necessary to explain detection of ‘Oumuamua chipped off from planetary surface requires heavy elements exceeding total quantity locked stars with 95% confidence, making scenario untenable because only small fraction...

Abstract Dynamical instabilities among giant planets are thought to be nearly ubiquitous, and culminate in the ejection of one or more into interstellar space. Here we perform N-body simulations dynamical while accounting for torques from galactic tidal field. We find that a fraction would otherwise have been ejected instead trapped on very wide orbits analogous those Oort cloud comets. The ran...