We have examined the development of self-peptide-specific CD4+ CD25+ regulatory T cells in lineages of transgenic mice that express the influenza virus PR8 hemagglutinin (HA) under the control of several different promoters (HA transgenic mice). By mating these lineages with TS1-transgenic mice expressing a TCR that recognizes the major I-E(d)-restricted determinant from HA (site 1 (S1)), we sh...

The CD44-negative T lymphoma AKR1 (CD44.2 genotype) was transfected with a CD44.1 cDNA. The intact cDNA conferred on the transfected cells the ability to bind hyaluronic acid (HA) both from solution and immobilized on culture plates. It also conferred a CD44-dependent and hyaluronidase-sensitive increase in adhesion to a lymph node endothelial cell line. A mutant cDNA which codes for a CD44 mol...

In order to study the effect of different levels of the manure and foliar application of Zn and Mn fertilizers on the quantitative and qualitative yield of soybeans (var. Williams), a factorial experiment was conducted in a randomized complete block design with three replications in 2012. Treatments involved three levels of fertilizer: manure (zero as control; six and 12 t/ha), two lev...

powdery mildew disease caused quality and quantity losses of sugar beet production. therefore, five spraying treatments and three sugar beet variety were conducted in split plot design with four reapplications during consecutive two years in kermanshah and mashhad regions. in order to control of disease, tridimorph fungicide was used. spraying treatments were in main plot and variety in the sub...

to estimate the optimum and effective amount of nitrogen fertilizer for quantity and quality improvement of three new durum wheat lines, this research was conducted in gachsaran dry-land agricultural research station for a duration of 4 years (2003-2007). the study was performed as a factorial expriment, using a randomized complete block design with 4 replications. two factors of: 4 nitrogen ra...

Field experiments were conducted in 2005-2006 and 2007-2008 and the data were used tocalibrate and validate yield and biomass of AquaCrop Model for canola (Brassica napus l.). Themodel was calibrated with the first year and then was validated with the second year data. Fivewater stress treatments at different growth stages were performed including fully irrigatedduring whole growing period (I1)...

Vegetative growth serves as an important means to capture and store atmospheric carbon dioxide in biomass and soil. Grassland soils are high in soil organic carbon and contain an extensive fibrous root system that creates an environment ideal for soil microbial activity. Accurate quantification of SOC pool is needed to generate benchmark information for the present and to determine the changes ...

Like cellular transplantation, gene therapy is often limited by immune rejection of the newly expressed antigen. In a model of gene transfer in muscle, delivery of the influenza hemagglutinin (HA) membrane protein by adeno-associated virus (AAV) is impaired by a strong immune response that leads to a rapid rejection of the transduced fibers. We show here that injection of HA-specific CD4+CD25+ ...

The yield responses of sugarcane to lime and gypsum at two sites in the KwaZulu-Natal Midlands of South Africa are presented and discussed. At Dalton, on a Magwa form soil with an initial aluminium saturation index (ASI) of >80%, over a plant and four ratoon crops variety N12 gave no significant response to dolomitic lime. By contrast, variety N16 gave consistent yield responses to lime at rate...