BACKGROUND Anaphylaxis is an emergency condition that requires immediate, accurate diagnosis and appropriate management. However, little is known about the level of knowledge of doctors and nurses treating these patients in the Emergency Department. OBJECTIVE To determine the knowledge of doctors and nurses in the Emergency Department on the recent definition and treatment recommendations of ...

The Food and Drug Administration (FDA) recently has re-released chymopapain, an injectable proteolytic enzyme used as an alternative to lumbar laminectomy in selected patients. The reported success rate, over 800%, has inspired an increasing usage of chymopapain. However, there is a reported 1 % incidence of anaphylaxis upon injection of this drug. The authors describe the means of early recogn...

Ranitidine is a well-tolerated H2-receptor antagonist commonly used in peptic ulcer treatment and stress ulcer prophylaxis. Anaphylaxis is rarely observed with ranitidine. We report the case of a patient who developed anaphylaxis after intravenous injection of ranitidine for acute COPD exacerbation. This article underlines the importance of awareness that in COPD acute exacerbation treatment, r...

There is increasing consumption of exotic food in Malaysia. Animals such as insects, worms and wild life animals also form part of the staple food of the local population. This practice may lead to more incidence of food allergy and anaphylaxis. We report a non-indigenous man who developed food anaphylaxis after consuming fried sago worms and consequently Takotsubo cardiomyopathy. We postulate ...

509 I n this issue of CMAJ, Brotherton and colleagues 1 report a comprehensive investigation revealing higher than expected rates of apparent anaphylaxis following vaccination with the quadrivalent human papillomavirus (HPV) vaccine in Australian children. The cause of these reactions remains somewhat unclear and needs further investigation. Of note, rates of anaphylaxis, if confirmed, may not ...

Aim: The aim of the study was to determinee the knowledge of dental students about signs, symptoms and management of anaphylaxis reaction to local anaesthetic drugs. Materials and Method: The study was designed with a pretested interviewer questionnaire containing 14 questions related to anaphylaxis to local anaesthesia in a private dental college. The interns and the postgraduates were randoml...

BACKGROUND Although currently misclassified in the International Classification of Diseases (ICD) and still not officially listed as a rare disease, anaphylaxis is a well-known clinical emergency. Anaphylaxis is now one of the principal headings in the "Allergic and hypersensitivity conditions" section recently compiled for the forthcoming 11th Revision of ICD (ICD-11). We here report the build...

INTRODUCTION Food-dependent exercise-induced anaphylaxis is a subtype of anaphylaxis and, although rare, it is an important condition to be familiar with as it can ultimately lead to death. CASE PRESENTATION We present a case of food-dependent exercise-induced anaphylaxis in a 17-year-old white girl due to chickpea. She had a history of anaphylaxis after eating crackers and hummus before exer...

The purpose of this investigation was to define and quantitatively evaluate cardiac anaphylaxis in vivo. Guinea pigs, passively sensitized with graded amounts of rabbit antipenicilloyl antibody, were anesthetized, ventilated, and challenged intravenously with a constant amount of antigen (anaphylaxis in vivo). In other experiments, guinea pig hearts were excised, perfused in a Langendorff appar...