A total of 24 nucleotides were examined as substrates for 5’-AMP aminohydrolase (EC 3.5.4.6). The following nucleotides were deaminated at the indicated maximum velocity relative to AMP (100): adenosine 5’-phosphoramidate (73), iV-methyl-AMP (ZO), dAMP (18), adenosine 5’-monosulfate (13), adenosine (l), and ADP (1). Other substrates for which maximum velocities were not determined included W-et...

The relationship between bradykinin (BK)-induced prostaglandin E2 (PGE2) and cyclic AMP syntheses in mouse fibrosarcoma cells (HSDM1C1) was investigated. Maximal BK-induced increases in cyclic AMP preceded increases in PGE2 production. PGE2 synthesis reached maximum at a much lower concentration of BK than cyclic AMP synthesis. Indomethacin completely inhibited BK-induced PGE2 production, but d...

The transimpedance or current feedback operational amplifier (CFB op-amp) is reviewed and compared to a conventional voltage mode op-amp using an analysis emphasizing the basic feedback characteristics of the circuit. With this approach the paradox of the constant bandwidth obtained from CFB op-amps is explained. It is demonstrated in a simple manner that the constant gain-bandwidth product of ...

This paper deals with chain graph models under alternative AMP interpretation. A new representative of an AMP Markov equivalence class, called the largest deflagged graph, is proposed. The representative is based on revealed internal structure of the AMP Markov equivalence class. More specifically, the AMP Markov equivalence class decomposes into finer strong equivalence classes and there exist...

To elucidate further how cyclic adenosine 3’ : S’-monophosphate (cyclic AMP) and the cyclic AMP receptor are able to stimulate gal mRNA synthesis we have utilized an antiserum specific for cyclic AMP receptor and also cyclic GMP as inhibitors of cyclic AMP and cyclic AMP receptor action. When cyclic AMP, cyclic AMP receptor, DNA, and RNA polymerase are incubated together a rifampicin-resistant ...

The effect of adenosine-3',5'-cyclic monophosphate (cyclic AMP) and N(6),O(2)-dibutyryl adenosine-3',5'-cyclic monophosphate (dibutyryl cyclic AMP) on renal tubular permeability was studied by microinjection techniques in anesthetized diuretic rats. Radioactive inulin and mannitol were microinjected simultaneously into superficial proximal and distal convolutions and recovery of the isotopes wa...

In order to provide a consistent explanation for Aristotelian modal syllogistic, this paper reveals the reductions between syllogism ◇I□A◇I-3 and other valid syllogisms. Specifically, on basis of formalizing syllogisms, proves validity by means truth value definition (modal) categorical propositions. Then in line with classical propositional logic logic, generalized quantifier theory set theory...

Abstract. The direct vapor equilibration laser spectrometry (DVE-LS) method has been developed for obtaining matrix-bound water stable isotope data in soils, the critical zone, and bedrock, deriving therefrom subsurface flow transport processes and, ultimately, characterizing, example, groundwater recharge vulnerability. Recently, DVE-LS increasingly adopted due to its possible high sample thro...

Laboratory and field experiments were performed to evaluate the pathogenicity of an isolate entomopathogenic fungus Metarhizium anisopliae two sympatrically occurring weevil species, Cylas formicarius Euscepes postfasciatus. In laboratory bioassays, suspension conidia, ≥106 CFU/mL, caused mortalities > 80% on adults both weevils in seven days after inoculation. It took longer time 20 for grain ...

The roles of cyclic AMP and cyclic AMP-dependent protein kinase in the contractile and metabolic responses to neural stimulation were studied in the bullfrog heart perfused in situ. The interaction of parasympathetic and sympathetic nerves in the regulation of myocardial cyclic AMP, cyclic AMP-dependent protein kinase, and phosphorylase also was studied. Stimulation of the left vagosympathetic ...