The tolerabilities of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole (TMP-SMX) suspensions were evaluated in 263 children with otitis media. Because of watery stools, therapy was discontinued in 6 of 83 patients treated with ampicillin, in none of 89 patients treated with amoxicillin (P less than 0.01), and in 1 of 91 patients treated with TMP-SMX (P less than 0.03). Of the patients...

Nowadays, antibiotics such as amoxicillin have been entered in water bodies. Nanofiltration has been proposed as an attractive technology for removal of antibiotics from aquatic environment instead of conventional wastewater treatment. In this paper, novel asymmetric flat sheet nanofiltration membranes were prepared via immersion precipitation technique and by using the poly(ethersulfone)/Brij®...

A reversed-phase column liquid chromatographic method was developed for the assay of amoxicillin and its preparations. The linear calibration range was 0.2 to 2.0 mg/ml (r = 0.9998), and recoveries were generally greater than 99%. The high-performance liquid chromatographic assay results were compared with those obtained from a microbiological assay of bulk drug substance and capsule, injection...

Ampicillin and amoxicillin (alpha-amino-p-hydroxybenzyl penicillin) were administered orally in 500-mg doses to eight fasting volunteers in a comparative study in which pharmacokinetic techniques were used. The absorption of amoxicillin was significantly better, as demonstrated by a higher mean peak serum concentration of 7.6 mug/ml as compared to 3.2 mug/ml for ampicillin, an average "area und...

Acute otitis media is the most common bacterial infection in pediatric patients. The predominant pathogens of acute otitis media are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Traditionally, amoxicillin has been the first-line therapeutic choice for patients with uncomplicated acute otitis media. However, with the increasing isolation of beta-lactamase-producin...

CONTEXT Evidence to support antibiotic treatment for acute rhinosinusitis is limited, yet antibiotics are commonly used. OBJECTIVE To determine the incremental effect of amoxicillin treatment over symptomatic treatments for adults with clinically diagnosed acute rhinosinusitis. DESIGN, SETTING, AND PARTICIPANTS A randomized, placebo-controlled trial of adults with uncomplicated, acute rhino...

introduction: the purpose of this study was to compare the setting time and post-setting solubility, flow, film thickness and dimensional changes of ah26 root canal sealer with ah26-antibiotic combination. materials and methods: this study was performed according to british standard bs 6876 (2001) which tests the physicochemical properties of endodontic sealers. three samples of each of tested ...

Four hundred sixty-six female patients were enrolled in a randomized study that compared the clinical efficacies of single oral doses of cefuroxime axetil and amoxicillin with probenecid in the treatment of uncomplicated gonorrhea. Two hundred ninety-five patients had culture-positive gonococcal infections and completed the investigation. Cure rates for the patients treated with cefuroxime axet...

Besides acting as antimicrobial compounds, dendrimers can be considered as agents that improve the therapeutic effectiveness of existing antibiotics. In this work we present a new approach to using amoxicillin (AMX) against reference strains of common Gram-negative pathogens, alone and in combination with poly(propylene imine) (PPI) dendrimers, or derivatives thereof, in which 100% of the avail...

OBJECTIVE To determine if amoxicillin/clavulanate potassium is effective in the treatment of Chlamydia trachomatis endocervicitis. METHODS Thirty-two patients with culture-proven endocervical infection were treated with amoxicillin/clavulanate potassium, 500 mg orally 3 times a day for 10 days. Post-treatment endocervical specimens were obtained at 2, 4, and 6 weeks for culture of C. trachoma...