This research develops a method for discovering functional sites of amino acid sequences using an Inductive Logic Programming (ILP) method with sorted variable generalization. Functional sites provide clues to building a knowledge base for prediction of protein functions from amino acid sequences. The proposed method generates hypotheses of functional sites directly from aligned amino acid sequ...

There are many amino acid sequences in proteomes which are not homologous to any other sequences. Therefore, methods to classify proteins independent of the sequence homology are strongly required for computational analysis of proteomes. Proteins may be divided into two categories: soluble and membrane proteins. Since membrane proteins are characterized by the existence of long hydrophobic tran...

There are many amino acid sequences in proteomes which are not homologous to any other sequences. Therefore, methods to classify proteins independent of the sequence homology are strongly required for computational analysis of proteomes. Proteins may be divided into two categories: soluble and membrane proteins. Since membrane proteins are characterized by the existence of long hydrophobic tran...

We have isolated and characterized complementary DNAs (cDNAs) encoding chicken cardiac muscle tropomyosin and a low-molecular-weight nonmuscle tropomyosin. The cardiac muscle cDNA (pCHT-4) encodes a 284-amino acid protein that differs from chicken skeletal muscle alpha- and beta-tropomyosins throughout its length. The nonmuscle cDNA (pFT-C) encodes a 248-amino acid protein that is most similar ...

Background and aims: The end of 2019 has marked the year, which the human population encountered a novel virus; SARS-CoV-2 that causes a disease namely COVID-19. Here we focused on the genome and protein mutations and subsequently suggested a new classification of the SARS-CoV-2. Materials and Methods: Our study showed that some extra positions in the virus genome play a key role in the SARS-C...

Gamma-amino butyric acid (GABA) possesses several physiological functions such as neurotransmission, induction of hypotension, diuretic and tranquilizer effects. Production of GABA-enriched products by lactic acid bacteria has been a focus of different researches in recent years because of their safety and health-promoting specifities. In this study, glutamate decarboxylase (gad) gene of a loca...