Ameloblastoma is the most common odontogenic neoplasm, particularized by its local invasiveness. Heparanase is the endo-glucuronidase enzyme that specifically cleaves heparan sulfate, the important modulator of extracellular matrix, and related to invasion of tumor cells. In this study, we addressed to show the gene expression and localization of heparanase in ameloblastoma. Immunohistochemistr...

Ameloblastoma is a true neoplasm of odontogenic origin and benign in nature. But it has a high percentage of local recurrence with possible malignant development when treated inadequately. The treatment planning in ameloblastomas is still not clear. We describe a case report of unicystic plexiform ameloblastoma in a young girl who was treated with conservative surgical management (enucleation &...

The peripheral ameloblastoma is a rare tumor of the oral cavity, of which relatively few well-documented cases have been reported. A 54-year-old Caucasian male was found to have such a lesion in the posterior maxilla. The origin, histological appearance, and surgical treatment of this lesion is discussed. Histologically, the peripheral ameloblastoma is indistinguishable from the basal cell carc...

Desmoplastic ameloblastoma (DA) is a relatively rare histological variant of ameloblastoma with specific clinical, radiological, and histological features. This tumor is more commonly seen in the anterior region of jaws as a mixed radiopaque-radiolucent lesion resembling benign fibro-osseous lesions. Histologically, DA is characterized by small nests and strands of "compressed" odontogenic epit...

We report the case of a 59-year-old woman who presented with metastatic ameloblastoma involving the lungs, 20 years after resection of the primary tumor in the mandible. The lesions were debulked on multiple occasions with radiofrequency ablation over an eight-year period with local response. There were no complications related to the procedures. We suggest that radiofrequency ablation is a pos...

Amebloblastoma as the most common epithelial odontogenic neoplasm may occur in two forms of central and peripheral. This report presents a case of a 41-year-old Iranian female with a six-month complaint from a painless mass in the right posterior portion of the mandible. The case was diagnosed as an exophytic epulis-like peripheral component with characteristics of peripheral ameloblastoma and ...

background and aims. odontogenic cysts and tumors have a wide spectrum of clinical characteristics that lead to the different management strategies. since definite diagnosis is difficult in some cases, it has been suggested that cd56 may be a candidate marker for definitive diagnosis of some odontogenic tumors. the present study was designed to examine cd56 expression in lesions with histopatho...

malignant transformation of ameloblastomas arising from an odontogenic cyst or de novo is wellrecognized. malignancies in ameloblastomas may involve metastasis or a local dysplastic change in the tissue. the latter are classified as ameloblastic carcinomas. a 75-year-old male presented with a mandibular cystic swelling, with no evidence of metastasis. dysplastic ameloblastic cells with spindlec...

Ameloblastoma is a benign tumor; whose importance lies in its potential to grow to enormous size with resulting bone deformity. Unicystic ameloblastoma (UA) is a less encountered variant of amelobastoma. The neoplastic nature of the lesion becomes evident only when the enucleated material is available for histologic examination. Although its predilection is for the posterior mandibular region, ...

OBJECTIVE The purpose of this study is to elicit the amount of safety margin necessary around the ameloblastic lesion in view of preventing further recurrence. MATERIALS AND METHODS The study consisted of 25 cases of mandibular ameloblastoma. Diagnosis was based on clinical and radiological analysis and confirmed by histopathological report. An incisional biopsy was done preoperatively to con...