In this study, we propose an adaptive multiscale ensemble (AME) learning approach, which consists of variational mode decomposition (VMD) and least square support vector regression (LSSVR) for seasonal trend forecasting tourist arrivals. the formulation AME original arrival series is decomposed into trend, seasonal, remaining volatility components. Then, ARIMA used to forecast component, SARIMA...

The human t(3;21)(q26;q22) translocation is found as a secondary mutation in some cases of chronic myelogenous leukemia during the blast phase and in therapy-related myelodysplasia and acute myelogenous leukemia. One result of this translocation is a fusion between the AML1, MDS1, and EVI1 genes, which encodes a transcription factor of approximately 200 kDa. The role of the AML1/MDS1/EVI1 (AME)...

Dihydrofolate reductase is markedly hyperproduced in strains of Diplococcus pneumoniae which bear any one of a unique group of sense to sense mutations (ame(r)) in the corresponding structural gene. Increased enzyme levels mediated by the ame(r) mutations are apparently the result of increased rates of de novo synthesis. The basis for these effects could be transcriptional, translational or cou...

The Otx2 gene encodes a paired-type homeobox transcription factor that is essential for the induction and the patterning of the anterior structures in the mouse embryo.Otx2 knockout embryos fail to form a head. Whereas previous studies have shown that Otx2 is required in the anterior visceral endoderm and the anterior neuroectoderm for head formation, its role in the anterior mesendoderm (AME) ...

In an attempt to study ways for reducing NOx emissions from radiatively/conductively-stabilized combustors (RCSC) for pulverized coal, a comprehensive conjugate heat and mass transfer and reaction kinetics model of that combustor was developed. As compared with a much simpler three-reaction model, the radiation intensity distribution obtained by the new model shows a substantial decrease in the...

Growing evidence indicates that the affinity of monoclonal antibodies (mAbs) for CD16 (Fc RIII) plays a central role in the ability of the mAb to mediate antitumor activity. We evaluated how CD16 polymorphisms, and mAb with modified affinity for target antigen and CD16, affect natural killer (NK) cell phenotype when CD20 malignant B cells were also present. The mAb consisted of rituximab (R), a...

The exposure to Alternaria toxins from grain and grain-based products has been reported to be related to human esophageal cancer in China. In this study, a total of 370 freshly harvested wheat kernel samples collected from Anhui province of China in 2015 were analyzed for the four Alternaria toxins tenuazonic acid (TeA), tentoxin (TEN), alternariol (AOH) and alternariol monomethyl ether (AME) b...

BACKGROUND The aim of this study was to explore the mechanism by which amentoflavone (AME) improves insulin resistance in a human hepatocellular liver carcinoma cell line (HepG2). METHODS A model of insulin resistant cells was established in HepG2 by treatment with high glucose and insulin. The glucose oxidase method was used to detect the glucose consumption in each group. To determine the m...

Generation of steady-state solid aerosol jets with controllable parameters is often necessary in experimental studies and industrial processes.Most of the current approaches use a  uidizedbed to produce an aerosol  owandalways introduce initial turbulence into the jet. Toproduce a laminar aerosol jet,  ow straighteners and long tubes are used that make the design cumbersome and in exible. I...

Two experiments were conducted to evaluate the nutritional value of three cultivars (Promore, Kiev mutant and Ultra) of white lupins (Lupinus albus L.) for broilers. In experiment 1, the apparent metabolisable energy (AME) and ileal amino acid digestibility coefficients of the three cultivars were determined. The cultivar effects were significant (P < 0.05) for AME, but the ileal amino acid dig...