A new simple high performance thin layer chromatographic method for simultaneous determination of antidiabetic drugs, metformin hydrochloride and sitagliptin phosphate in bulk and tablet dosage form were investigated. Chromatographic separation of the drugs were performed on aluminum plates precoated with silica gel 60 F254 as the stationary phase and the solvent system consisted of acetone:met...

tiydroxylation of monacolin L to monacolin J by M. ruberlt8). The present communication deals with the transformation of monacolin J to monacolin K by a cell-free extract of M. ruber and by living cells of Paecilomyces viridis. The latter fungus is known to produce compactin (ML-236B) analogs, another family of HMG-CoAreductase inhibitors6). M. ruber M4681 was grown aerobically in a medium cont...

For fast detection of inorganic phosphorus fractions and their phosphorus contents in soil, a method employing near-infrared spectroscopy (NIRS) combined with partial least squares (PLS) and least squares support vector machine (LS-SVM) was proposed. Fifty soil samples for each of iron phosphate, magnesium phosphate, calcium phosphate and aluminum phosphate, with application rates of phosphate ...

Accumulation of inorganic phosphate due to renal functional impairment contributes to the increased cardiovascular mortality observed in dialysis patients. Phosphate plays a causative role in the development of vascular calcification in renal failure; treatment with calcium-based phosphate binders and vitamin D can further increase the Ca x PO(4) product and add to the risk of ectopic mineraliz...

If a filtered bacteria-free phage lysate of a broth culture of coli bacteria is shaken with aluminum oxide C g, the phosphate-containing high-molecular phage protein is adsorbed preferentially. It can be eluted again from the centrifuged and washed adsor-bant by means of a phosphate buffer (m/10 to m/30, pH 7). This adsorption procedure is repeated several consecutive times on the lysate [and] ...

Hydroxyapatite/alpha-alumina composites were prepared by means of high-energy vibratory ball milling. The effect of the addition of alumina, from 5 to 25 wt%, was investigated. x-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR) results indicated thathydroxyapatite andaluminawere themajorphases aftermechanicalmilling and only small peak shifts were observed. Transmission...

This method was developed for the determination of trace amounts of aluminum(III) in dialysis concentrates using atomic absorption spectrometry after coprecipitation with lanthanum phosfate. The analytical parameters that influenced the quantitave coprecipitation of analyte including amount of lanthanum, amount of phosfate, pH and duration time were optimized. The % recoveries of the analyte io...

The efficiencies of the restoration two lakes varied morphometries and trophic states—meromictic, hypertrophic Lake Klasztorne Ma?e, dimictic, eutrophic Du?e—with use phosphorus inactivation method with sequential application iron aluminum compounds have been compared. total dose agents applied for Ma?e was 38 tons PAX 18 (aluminum polychloride) 14 PIX 111 (iron chloride), Du?e, it 74 46 111. A...

In this study, we used a novel composite material based on magnesium phosphate cement (MPC) to explore the retention of fluoride from water. Dead-burned oxide (MgO), ammonium dihydrogen (NH4H2PO4), and few retarders were create particular substance. Several studies have corroborated performance using aluminum in capture fluoride. From perspective, attempted reinforce our matrix with different q...

Arterial calcification (AC) is a common complication of end-stage renal disease (ESRD). The mechanisms responsible are complex, including disturbances of mineral metabolism and active expression of various mineral-regulating proteins. An inverse relationship between AC and bone density has been documented in uremic patients. In the study presented here, which included 58 patients with ESRD on h...