نتایج جستجو برای: altitude pulmonary hypertension

تعداد نتایج: 369666  

Journal: :Journal of applied physiology 1996
G R Kleger P Bärtsch P Vock B Heilig L J Roberts P E Ballmer

A potential pathogenetic cofactor for the development of acute mountain sickness and high-altitude pulmonary edema is an increase in capillary permeability, which could occur as a result of an inflammatory reaction and/or free radical-mediated injury to the lung. We measured the systemic albumin escape by intravenously injecting 5 muCi of 125I-labeled albumin and the plasma concentrations of cy...

Journal: :The European respiratory journal 2005
R Fischer S M Lang K Brückner H-X Hoyer S Meyer M Griese R M Huber

Current guidelines for air travel state that patients with chronic respiratory diseases are required to use oxygen if their in-flight arterial oxygen tensions (Pa,O2) drop below 6.6 kPa. This recommendation may not be strictly applicable to cystic fibrosis patients, who may tolerate lower Pa,O2 for several hours without clinical symptoms. Lung function, symptoms, blood gas levels and signs of p...

Journal: :The Journal of clinical investigation 1988
T J Stelzner R F O'Brien K Sato J V Weil

Pulmonary edema after ascent to altitude is well recognized but its pathogenesis is poorly understood. To determine whether altitude exposure increases lung vascular permeability, we exposed rats to a simulated altitude of approximately 14,500 feet (barometric pressure [Pb] 450 Torr) and measured the pulmonary transvascular escape of radiolabeled 125I-albumin corrected for lung blood content wi...

Journal: :iranian journal of basic medical sciences 0
shi-huan yu institute of pulmonary disease, the first hospital of china medical university, shenyang, china, 110001first hospital of harbin medical university, harbin, china, 150001 jing-ying chen first hospital of harbin medical university, harbin, china, 150001 yi-mei zhang first hospital of harbin medical university, harbin, china, 150001 gui-wei jiao first hospital of harbin medical university, harbin, china, 150001 feng-qi liu first hospital of harbin medical university, harbin, china, 150001 ling-fei kong first hospital of harbin medical university, harbin, china, 150001

objective(s): the present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. materials and methods: forty eight wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. animals were placed in a hypoxia chamber and instrumented with epidural catheters at the th...

2015
Tsering Norboo Tsering Stobdan Norboo Tsering Norboo Angchuk Phunsog Tsering Iqbal Ahmed Tsewang Chorol Vijay Kumar Sharma Prasanna Reddy Shashi Bala Singh Yumi Kimura Ryota Sakamoto Eriko Fukutomi Motonao Ishikawa Kuniaki Suwa Yasuyuki Kosaka Mitsuhiro Nose Takayoshi Yamaguchi Toshihiro Tsukihara Kozo Matsubayashi Kuniaki Otsuka Kiyohito Okumiya

OBJECTIVE Prevalence of hypertension was examined in a widely dispersed (45 110 km(2)) representative group of Ladakhi in Northern India. The influence of hypoxic environment of wide-ranged altitude (2600-4900 m) and lifestyle change on hypertension was studied. METHODS 2800 participants (age 20-94 years) were enrolled. Systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure of ≥90...

2015
Cuomu Mingji Igho J Onakpoya Rafael Perera Alison M Ward Carl J Heneghan

INTRODUCTION Hypertension is a leading cause of cardiovascular disease, which is the cause of one-third of global deaths and is a primary and rising contributor to the global disease burden. The objective of this systematic review was to determine the prevalence and awareness of hypertension among the inhabitants of Tibet and its association with altitude, using the data from published observat...

Background: Children with congenital heart disease (CHD) are prone to malnutrition and growth retardation. This study aimed to compare growth status between children with CHD and healthy children.                Materials and Methods: This case–control study included 310 children with CHD and 300 healthy children matched in age and gender. CHD patients grouped according to cardiac diagnosis: ...

Journal: :High altitude medicine & biology 2013
Piergiuseppe Agostoni

Prognosis and quality of life of chronic heart failure (HF) patients have greatly improved over the last decade. Consequently, many patients are willing to spend leisure time at altitude, usually <3500 m, but their safety in doing so is undefined. HF is a syndrome that often has relevant co-morbidities, such as pulmonary hypertension, COPD, unstable cardiac ischemia, and anemia. HF co-morbiditi...

Background: Vitamin D (Vit D) is linked to various conditions including musculoskeletal, metabolic and&nbsp;&nbsp; cardiopulmonary diseases. However, it is not clear whether correction of vit D deficiency exerts any beneficial effect in patients with pulmonary hypertension. Methods: This study was a prospective uncontrolled longitudinal study. Patients with pulmonary hypertension and vit D d...

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