OBJECTIVE Pediatric obesity commonly co-exists with emotional and behavioral disorders, while disturbed cortisol concentrations have been reported in both obese and chronically stressed individuals with anxiety and/or depression. We investigated the prevalence of internalizing and externalizing problems, reported by both parents and children, in a clinical population of obese children (OC) comp...

BACKGROUND & AIMS Increased visceral adiposity is considered the hallmark of the metabolic syndrome, whose hepatic manifestation is nonalcoholic fatty liver disease (NAFLD), although a subset of patients does not have visceral obesity. Our study aimed to compare metabolic alterations and liver damage in patients with NAFLD with and without visceral obesity. METHODS Four hundred and thirty one...

Objective: The prevalence of obesity is rising in both developed and developing countries. Globally, it is estimated that nearly one billion adults are overweight at least 300 million of them are clinically obese. In Afghanistan no published data is available regarding non-communicable diseases including obesity. This paper reports the prevalence and associated risk factors of obesity among adu...

We conducted this study to determine the degree of obesity influence on the hypoglycemic response of growth hormone and cortisol after weight loss of 5%. A total of 45 non-diabetic, male subjects followed in the outpatient endocrinological departments were divided into three groups comprising 15 subjects in each group, based upon body mass index (BMI) to healthy, overweight and obese group. Met...

background: simultaneous electrocardiographic (ecg) changes are seen in hemorrhagic brain events even in the absence of associated myocardial infarction (mi). this study was designed to assess the role of ecg changes to predict true mi in patients with hemorrhagic brain trauma. methods: data of 153 patients with traumatic brain injury and concomitant ecg changes were recorded. enzyme study was ...

In a recent issue of the Journal, Drs. Reaven and Tsao (1) discussed the association between cigarette smoking and insulin resistance, endothelial dysfunction, and dyslipidemia. They assert that insulin resistance may be a key mechanism by which smoking increases the risk of atherosclerotic cardiovascular disease. We agree with this assertion and suggest that elevated glucocorticoid tone may be...

BACKGROUND Prior research indicates that blacks and Hispanics/Latinos have flatter diurnal cortisol declines across the day, a profile associated with poorer health. The stability of racial and ethnic differences in cortisol levels over time is not well understood, and additional research is needed to establish racial and ethnic differences in psychosocial stress levels as related to changes in...