Background Athletes use ergogenic aids in an attempt to increase training-adaptations, which serves to enhance their performance during competition. Creatine monohydrate is one of the most studied ergogenic aids. Although many studies have reported the efficacy and effectiveness of creatine monohydrate supplement manufacturers continually introduce newer forms of creatine into the marketplace. ...

1. Concentrations of ketone bodies, free fatty acids and chloride in fed, 24-120h-starved and alloxan-diabetic rats were determined in plasma and striated muscle. Plasma glucose concentrations were also measured in these groups of animals. 2. Intracellular metabolite concentrations were calculated by using chloride as an endogenous marker of extracellular space. 3. The mean intracellular ketone...

The aim of this study is to investigate the hydration and the dehydration processes of calcium benzoate hydrates (trihydrate and monohydrate), thermotropic mesophases (dehydrated mesophase and lyophilized mesophase) and amorphous state, and the influence of their molecular order on those processes. X-ray analysis revealed that trihydrate has a planar structure composed of two types of planes-on...

Background & Aim: Diabetes mellitus often has been referred to as a syndrome of disordered metabolism, usually due to a combination of hereditary and environmental causes, resulting in abnormal of high blood sugar levels (hyperglycemia). Nowadays, no-drug treatments (medicinal plants) are novel therapeutic approaches in the treatment of diabetes. Experimental: This study aimed at assessing the...

Glycosaminoglycan (GAG) has a pivot role in renal function and homeostasis. Analysis of GAG amount generally serves to determine GAG alteration due to diabetes mellitus. Critical Electrolyte Concentration (CEC) staining can be an efficacy method to study GAG amount changes. Based on an experimental study, 20 male rats were randomly divided equally into two experimental and control groups. Diabe...

Healing of skin wound is a multi-factorial and complex process. Proper treatment of diabetic wounds is still a major clinical challenge. Although diabetes mellitus can occur in ruminants, healing of wounds in diabetic ruminants has not yet been investigated. The aim of this study was to evaluate healing of ovine excisional diabetic wound model. Eight 4-month-old Iranian Makoui wethers were equa...

Our objective was to determine the effect of creatine monohydrate on disease progression in patients with amyotrophic lateral sclerosis (ALS). One hundred and seven patients with the diagnosis of probable or definite ALS, of less than five years duration from symptom onset, were randomized to either treatment with daily creatine monohydrate (5 g/d) or placebo. In this multicenter, double-blinde...

Objective: Medical plants, as rich sources of natural antioxidants with antidiabetic effects, are used worldwide to diminish a variety of symptoms and many diseases. R. ribes L., which belongs to the family of polygonaceae, can provide symptomatic relief and assist in the prevention of the secondary complications of the diabetes. Material and Methods: 36 female adult rats were randomly divided ...

Background & Aim: Diabetes mellitus often has been referred to as a syndrome of disordered metabolism, usually due to a combination of hereditary and environmental causes, resulting in abnormal of high blood sugar levels (hyperglycemia). Nowadays, no-drug treatments (medicinal plants) are novel therapeutic approaches in the treatment of diabetes. Experimental: This study aimed at assessing the...

Effect of continuous administration of dried 75% methanolic extract of fruits of Terminalia belerica (Combretaceae) suspended in water was studied in alloxan induced hyperglycemia and antioxidant defense mechanism in rats. T. belerica prevented alloxan-induced hyperglycaemia significantly from 6th day of administration and there was 54% reduction on 12th day. Oxidative stress produced by alloxa...