نتایج جستجو برای: allogeneic stem cell transplantation

تعداد نتایج: 1894343  

2014
Israel Henig Tsila Zuckerman

Hematopoietic stem cell transplantation is a highly specialized and unique medical procedure. Autologous transplantation allows the administration of high-dose chemotherapy without prolonged bone marrow aplasia. In allogeneic transplantation, donor-derived stem cells provide alloimmunity that enables a graft-versus-tumor effect to eradicate residual disease and prevent relapse. The first alloge...

Journal: :Haematologica 2010
José Luis Piñana Rodrigo Martino Jorge Gayoso Anna Sureda Javier de la Serna Jose Luis Díez-Martín Lourdes Vazquez Reyes Arranz José Francisco Tomás Antonia Sampol Carlos Solano Julio Delgado Jorge Sierra Dolores Caballero

BACKGROUND Allogeneic hematopoietic stem cell transplantation is an effective treatment for patients with poor risk lymphoma, at least in part because of the graft-versus-lymphoma effect. Over the past decade, reduced intensity conditioning regimens have been shown to offer results similar to those of conventional high-dose conditioning regimens but with lower toxicity early after transplantati...

Journal: :The hematology journal : the official journal of the European Haematology Association 2003
Abderrahman Abdelkefi T Ben Othman S Ladeb L Torjman A Ben Abdeladhim

Rejection after allogeneic bone marrow transplantation for Fanconi anemia (FA) is a complication with a high risk of mortality. We describe a patient who, following a second episode of rejection after a second allogeneic stem cell transplantation, was successfully treated with antilymphocyte globulin, followed by donor lymphocyte infusion. At three and a half years after donor lymphocyte infusi...

Journal: :Haematologica 2011
Martin Schmidt-Hieber Julie Schwender Werner J Heinz Tatjana Zabelina Jörn S Kühl Sabine Mousset Silke Schüttrumpf Christian Junghanss Gerda Silling Nadezda Basara Stefan Neuburger Eckhard Thiel Igor W Blau

BACKGROUND Limited data are available on characteristics of viral encephalitis in patients after allogeneic stem cell transplantation. DESIGN AND METHODS We analyzed 2,628 patients after allogeneic stem cell transplantation to identify risk factors and characteristics of viral encephalitis. RESULTS Viral encephalitis occurred in 32 patients (1.2%, 95% confidence interval 0.8%-1.6%) and was ...

Journal: :Haematologica 2009
Lucia Farina Cristiana Carniti Anna Dodero Antonio Vendramin Anna Raganato Francesco Spina Francesca Patriarca Franco Narni Fabio Benedetti Attilio Olivieri Paolo Corradini

BACKGROUND The graft-versus-leukemia effect is able to induce clinical responses in patients with chronic lymphocytic leukemia treated with a reduced intensity conditioning regimen, followed by allogeneic stem cell transplantation. We investigated whether molecular remissions could be attained after reduced intensity conditioning and allogeneic stem cell transplantation in patients with relapse...

Journal: :Best Practice & Research Clinical Haematology 2011

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