abstract necrotizing sarcoid granulomatosis (nsg) is a rare disease which is classified in the spectrum of pulmonary angiitis and granulomatosis. it is a variant of sarcoidosis and differs from it histologically. diagnosis is based on the pathological features, but radiology may help in the differential diagnosis. it is characterized by alveolar infiltrates or parenchymal nodules in multidetect...

Background: Psychological factors can be associated with allergic disorders. However, no particular personality pattern associated with these disorders has yet been identified. Objectives: This study aimed at comparing the personality profiles of patients with perennial allergic rhinitis and normal controls. Materials & Methods: This cross-sectional study was done on 50 adult people with pe...

background: occupational contact dermatitis, especially in hand, is one of the most common occupational disorders. the present study aimed at evaluating patients with occupational allergic contact dermatitis (acd) caused by common allergens based on occupation type and disease history.   methods: this cross-sectional study aimed at evaluating the data of the patients with probable diagnosis of ...

Introduction Granulomatosis with polyangiitis (GPA) is a necrotising granulomatous vasculitis affecting the small and medium blood vessels in particular of airways and kidneys. The incidence of GPA in Europe is 25-150 per 1 million per year. This disease typically occurs in the 4th or 5th decades of life and in children it usually cause diagnostic and therapeutic difficulties. Subglottic stenos...

allergen immunotherapy involves the administration of gradually increasing quantities of specific allergens to patients with ige-mediated conditions until a dose is reached that is effective in reducing disease severity from natural exposure. in the present study we evaluated a period of six years immunotherapy allergic rhinitis and allergic asthma patients with positive skin prick test of comm...

Herpes zoster ophthalmicus can be complicated by a delayed ipsilateral cerebral angiitis which may cause infarction and a smoldering meningoencephalitis. We describe such a case treated successfully with steroids and acyclovir. It is important to consider the diagnosis of this disorder early since therapeutic intervention may prevent an otherwise high morbidity and mortality. Steroids may have ...

An 1-year-old dog succumbed to a seizure disorder of 18 days duration. At necropsy, an area of hemorrhage and discolored parenchyma was identified in the left pyriform lobe of the brain. Microscopic examination revealed a localized, necrotizing vasculitis with associated cerebral necrosis. Vasculitis was not present in other organs. This presentation is consistent with isolated central nervous ...

Background Primary angiitis of the central nervous system in children (cPACNS) is an inflammatory vasculitis that solely affects the CNS vessels in the absence of a systemic inflammatory process. Circulating endothelial cells (CECs) are increasingly described as biomarkers for tracking vascular injury [1]. Additionally, bone marrow-derived endothelial progenitor cells (EPCs) are thought to play...

asthma is a global problem that affects over 300 million people in the world. the main reason of asthma is allergy and atopy. asthmatic patients are sensitized to allergens that can be resulting asthma attacks. fungi as an allergen can be sensitized atopic people and present a severe asthma. fungi have been found in water-damaged homes of asthmatic patients. allergic asthma is associated with e...