BACKGROUND Triple infection (TI) with HIV-1, HCV, and HBV (TI) is highly prevalent in intravenous drug users (IDUs). These TI patients have a faster progression to AIDS, and even after antiretroviral therapy (ART) the prognosis of their disease is poor. The use of microRNA (miRNA) to silence genes holds potential applications for anti-HCV therapy. METHODS We analyzed the role of human miRNAs ...

Three-dimensional electron backscatter diffraction data, obtained by serial sectioning a nickel– base superalloy, has been analysed to measure the geometric arrangement of grain boundary planes at triple junctions. This information has been used to calculate the grain boundary character distribution (GBCD) and the grain boundary energy distribution (GBED). The twin content from the three-dimens...

Many production activities require cooperation between agents in an organization, and incentive alignment may take advantage of complementarities in such activities. This paper investigates such a possibility by examining two education policies that were implemented in New York City: a grade retention policy that incentivizes students and an accountability scheme that incentivizes schools. I em...

  Background: The prevalence of hip dysplasia is 1 in 1000. Several pelvic osteotomy methods have been developed to prevent early osteoarthritis, such as triple osteotomy. In this study we are going to introduce our new technique that was done on 4 patients with favorable short-term results.   Methods: Four patients underwent triple osteotomy and fixation using a reconstruction plate and early ...

background: selection of the best approach for the treatment of helicobacter pylori (h. pylori) infection that encompasses higher eradication and lower failure rates leads to a decline in its related complications and disorders. to understand the relative efficacy of new sequential therapy compared with standard triple therapy as two common regimens, we have performed a randomized, controlled t...

We present a high sensitivity single-monochromator Raman spectrometer which allows operation with a tunable laser source. The instrument is based on the modification of a commercial Raman spectrometer; such instruments operate with interference Rayleigh filters which also act as laser mirrors and are usually considered as inherently narrow band. In our design, the two tasks are separated and th...

We present the contextual tag cloud system, where the context defines a subset of instances, the tags are ontological terms (classes and properties), and the font sizes reflect the number of instances that use each tag. With our system, users can get familiar with the terms and understand how the dataset is populated; or they can dynamically add tags as context and investigate features or look ...

Triple resonance E.COSY-based techniques were used to measure intra-residue and sequential H(N)-H(alpha) residual dipolar couplings (RDCs) for the third IgG-binding domain of protein G (GB3), aligned in Pf1 medium. Measurements closely correlate with values predicted on the basis of an NMR structure, previously determined on the basis of a large number of one-bond backbone RDCs measured in five...