Non alcoholic fatty liver disease occurs in those who don't consume alcohol in amounts considered harmful to the liver. It represents a spectrum of conditions characterized histologically by mainly macrovesicular hepatic steatosis. There are two histological patterns of NAFLD: fatty liver alone and steatohepatitis. In this brief review, clinical and histologic spectrum, natural history, diagnos...

BACKGROUND Some risk factors for atherosclerosis are followed by non-alcoholic fatty liver disease (NAFLD). We wanted to use Multislice computed tomography (MSCT) as technique for searching relationship between NAFLD and coronary artery disease (CAD). OBJECTIVE The relationship between NAFLD and CAD was investigated using MSCT. METHODS A total of 372 individuals with or without cardiac symp...

Non-alcoholic fatty liver disease (NAFLD) comprising hepatic steatosis, non-alcoholic steatohepatitis (NASH), and progressive liver fibrosis is considered the most common liver disease in western countries. Fatty liver is more prevalent in overweight than normal-weight people and liver fat positively correlates with hepatic insulin resistance. Hepatic steatosis is regarded as a benign stage of ...

Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming the most common chronic liver disease worldwide, afflicting 20-30% of the general population of western countries [1]. It is also currently the most common liver disease in children [2]. NAFLD refers to a wide spectrum of liver damage, which begins with simple steatosis (accumulation of triglyceride filled vesicles in liver cells), a...

Non-alcoholic fatty liver disease (NAFLD) covers a spectrum of lesions ranging from steatosis (Non-alcoholic Fatty Liver or NAFL) to a complex pattern with hepatocellular injury and inflammation (non-alcoholic steatohepatitis; NASH) in the absence of alcohol intake. However, it is increasingly clear that intermediate patterns may exist. The histopathological evaluation of liver biopsy samples i...

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic disease, affecting approximately 2 billion individuals worldwide with a spectrum that can range from simple steatosis to cirrhosis. Typically, diagnosis NAFLD based on imaging studies, but gold standard remains biopsies. Hence, use artificial intelligence (AI) in this field, which has recently undergone rapid devel...

In patients with chronic liver disease, especially nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD) and chronic hepatitis C, iron overload is an important factor for the severity and course of disease. The clinical benefit of phlebotomy as iron reduction therapy in patients with NAFLD and ALD and iron is not clear yet. The aim of our study was to evaluate the effect of ph...

Abbreviations: HE: Hepatic Encephalopathy; PAMPs: Pathogen associated molecular patterns; TLRs: Toll-like Receptors; NLRs: Nodlike Receptors; LPS: Lipopolysacharide; HCV: Hepatitis C virus; CHB: Chronic Hepatitis B; HBV: Hepatitis B virus; ALD: Alcoholic Liver Disease; BM: Bone Marrow; NAFLD: Nonalcoholic Fatty Liver Disease; NASH: Non-alcoholic steatohepatitis; NO: Nitric Oxide; SIRS: Systemic...

As the number of individuals with non-alcoholic fatty liver disease (NAFLD) has increased, the influence of NAFLD on other metabolic diseases has been highlighted. Accumulating epidemiologic evidence indicates that NAFLD not only affects the liver but also increases the risk of extra-hepatic diseases such as type 2 diabetes mellitus, metabolic syndrome, dyslipidemia, hypertension, cardiovascula...