In Parkinson's disease patients in the OFF medication state, basal ganglia local field potentials exhibit changes in beta and gamma oscillations that correlate with reduced voluntary movement, manifested as rigidity and akinesia. However, magnetoencephalography and low-resolution electrocorticography (ECoG) studies in Parkinson's patients suggest that changes in sensorimotor cortical oscillatio...

Tako-tsubo syndrome is a disease with similar alterations to ose observed in acute myocardial infarctions in the absence of ronary stenosis. Several pathophysiological mechanisms have en proposed to explain the unusual features of this syndrome, ch as multivessel coronary vasospasm, abnormalities in ronary microvascular function, and catecholamine-mediated rdiotoxicity. Inflammation may also pl...

PURPOSE To compare the intraoperative and postoperative clinical properties of 1% ropivacaine, 0.75% bupivacaine, 2% lidocaine and a mixture of 0.75% bupivacaine and 2% lidocaine (bupi+lido) administered for peribulbar anaesthesia during vitrectomy. METHODS A total of 140 patients were randomly allocated to four groups. The time of onset of analgesia and akinesia was measured. The efficacy of...

A series of 198 consecutive patients with acute myocardial infarction were prospectively studied before hospital discharge and during 24.0 t 8.6 months of follow-up. A predischarge i irombus was found In 38 (31%) of 124 patients with anterior Infarction but in none of 74 patients with inferior infarction (p < 0 .001) . Early thrombolytic therapy in 34 patients did not decrease the rate of throm...

The aim of this study was to investigate the potential antidepressive-like effect of tetramethylpyrazine (TMP), one of available blood-activating and stasis-eliminating components from traditional Chinese medicines, and its mechanism of the antidepressant-like action. Forced-swimming, tail-suspension, reserpine-induced hypothermia, akinesia and ptosis, 5-hydroxytryptophan (5-HTP)-induced head-t...

OBJECTIVE To study planning of movement in Parkinson's disease. METHODS The spatiotemporal pattern of movement related desynchronisation (MRD) preceding a self paced voluntary wrist flexion was compared between two groups of 10 untreated right and left hemiparkinsonian patients receiving no treatment and 10 control subjects. The MRD was computed in the 9 to 11 Hz frequency band from 11 source...