INTRODUCTION Pre-hospital airway management is a key component of resuscitation although the benefit of pre-hospital intubation has been widely debated. We report a large series of pre-hospital emergency airway encounters performed by air-transport providers in a large, multi-state system. METHODS We retrospectively reviewed electronic intubation flight records from an 89 rotorcraft air medic...

Airway hyperresponsiveness (AHR) is a defining characteristic of asthma that refers to the capacity of the airways to undergo exaggerated narrowing in response to stimuli that do not result in comparable degrees of airway narrowing in healthy subjects. Airway smooth muscle (ASM) contraction mediates airway narrowing, but it remains uncertain as to whether the smooth muscle is intrinsically alte...

Surgical correction of obstructive sleep apnea (OSA) syndrome involves understanding a number of parameters, of which the 3-dimensional airway anatomy is important. Visualization of the upper airway based on cone beam computed tomography scans and automated computer analysis is an aid in understanding normal and abnormal airway conditions and their response to surgery. The goal of surgical trea...

BACKGROUND Morbidly obese patients are at elevated risk of perioperative pulmonary complications, including airway obstruction and atelectasis. Continuous positive airway pressure may improve postoperative lung mechanics and reduce postoperative complications in patients undergoing abdominal surgery. METHODS Forty morbidly obese patients with known obstructive sleep apnea undergoing laproscop...

BACKGROUND Airway responsiveness to histamine and methacholine, direct smooth muscle spasmogens, is increased following inhalation of allergen. Although the aetiology of this phenomenon is unclear, increased cellular or neural activity may be involved since allergen also induces increases in airway responsiveness to the mast cell stimulus adenosine-5'-monophosphate (AMP) and the neural stimulus...

An imaging-based computational framework for simulation of airflow in subject specific breathing human lungs is established. The three-dimensional (3D) airways of up to 9 generations and lobes are segmented and reconstructed from computed tomography (CT) images. Beyond the CT-resolved 3D airways, a volume filling method is applied to generate the one-dimensional (1D) conducting airway tree that...

Correspondence To the Editor: In a single‑center, prospective, randomized double‑blind clinical study comparing dexmedetomidine‑ midazolam and sufentanil‑midazolam sedation regimens for awake fiberoptic intubation (AFOI) in 50 patients with difficult airways due to limited mouth opening, Li et al. show that both dexmedetomidine and sufentanil are effective as an adjuvant for AFOI under airway t...

Objective: Asthma is an airway complex disease defined by reversible airway narrowing and obstruction, chronic airway inflammation, airway hyperresponsiveness, and tissue remodeling. The purpose of this study was to determine the effect of Brassica napus L. (B. napus) on airway pathologic changes in a rat model of asthma. Materials and Methods: Twenty-four rats were divided into 4 groups: contr...

The chance of developing lung cancer is increased through being exposed to cigarette smoke illustrated by studies. It is vital to understand the development of particular histologic-type cancers regarding the deposition of carcinogenic particles, which are present in human airway. In this paper, the mass transfer and deposition of cigarette smoke, inside the human airway, are investigated apply...