نتایج جستجو برای: aio

تعداد نتایج: 294  

Journal: :Digestive diseases 2005
J Souglakos N Vardakis N Androulakis S Kakolyris Ch Kouroussis D Mavroudis A Pallis S Agelaki K Kalbakis V Georgoulias

PURPOSE A phase II study was conducted to evaluate the toxicity and efficacy of irinotecan (CPT-11), 5-fluorouracil/leucovorin (5-FU/LV) (AIO regimen) as salvage treatment in patients with metastatic colorectal cancer (MCC). PATIENTS AND METHODS Thirty-three patients relapsing after oxaliplatin-based first line chemotherapy were enrolled. There were 20 males and 13 females with median age of ...

2014
Katrin Hug William A. Maher Matthew B. Stott Frank Krikowa Simon Foster John W. Moreau

Acid-sulfide hot springs are analogs of early Earth geothermal systems where microbial metal(loid) resistance likely first evolved. Arsenic is a metalloid enriched in the acid-sulfide hot spring Champagne Pool (Waiotapu, New Zealand). Arsenic speciation in Champagne Pool follows reaction paths not yet fully understood with respect to biotic contributions and coupling to biogeochemical sulfur cy...

2005
Byung Chun Kim

PURPOSE We assessed the impact of tumor regression grading (TRG) and its value in correlation to established prognostic factors in a cohort of rectal carcinoma patients treated by preoperative chemoradiotherapy (CRT). PATIENTS AND METHODS TRG was evaluated on surgical specimens of 385 patients treated within the preoperative CRT arm of the CAO/ARO/AIO-94 trial: 50.4 Gy was delivered, fluorour...

2010
Aru W Sudoyo

INTRODUCTION Colorectal cancer (CRC) ranks among the 10 most common cancers in the world,1 including Indonesia.2 It is the most environmentally-related cancer and in this country sporadic CRC affects 35.2% of people below 40 years old,2 as compared to only 3% in developed countries,3 making it an increasingly important health issue as the disease deprives the country of resources and productivi...

2011
Kathrin Koucky Axel Wein Peter C. Konturek Heinz Albrecht Udo Reulbach Gudrun Männlein Kerstin Wolff Nicola Ostermeier Dagmar Busse Henriette Golcher Claus Schildberg Rolf Janka Werner Hohenberger Eckhart G. Hahn Jürgen Siebler Markus F. Neurath Frank Boxberger

BACKGROUND The aim of this retrospective study was to evaluate the efficacy and safety of weekly high-dose 5-fluorouracil (5-FU)/folinic acid (FA) as 24-h infusion (AIO regimen) plus irinotecan in patients with histologically proven metastatic gastroesophageal adenocarcinoma (UICC stage IV). MATERIAL/METHODS From 08/1999 to 12/2008, 76 registered, previously untreated patients were evaluable....

Journal: :Gut 2013
Volker Heinemann Ursula Vehling-Kaiser Dirk Waldschmidt Erika Kettner Angela Märten Cornelia Winkelmann Stefan Klein Georgi Kojouharoff Thomas C Gauler Ludwig Fischer von Weikersthal Michael R Clemens Michael Geissler Tim F Greten Susanna Hegewisch-Becker Oleg Rubanov Gerold Baake Thomas Höhler Yon D Ko Andreas Jung Sascha Neugebauer Stefan Boeck

OBJECTIVE AIO-PK0104 investigated two treatment strategies in advanced pancreatic cancer (PC): a reference sequence of gemcitabine/erlotinib followed by 2nd-line capecitabine was compared with a reverse experimental sequence of capecitabine/erlotinib followed by gemcitabine. METHODS 281 patients with PC were randomly assigned to 1st-line treatment with either gemcitabine plus erlotinib or cap...

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