Background Myoclonus and encephalopathy are unusual in patients with Parkinson's disease (PD). Case report We describe the case of a 59-year-old male with PD who developed myoclonus and encephalopathy. Underlying hypothyroidism was revealed after admission and treated with levothyroxine. Myoclonus and encephalopathy were completely resolved following thyroid hormone replacement. Discussion ...

Patients suffering from endocrine disorders, which affect the function of central nervous system, need a special care and approach in the process of smoking cessation. The process of informing about negative effects of smoking addiction, including potential aggravation of the disease, has to be specially tailored to the need of the patient and the type of the disease. The informing physician sh...

The authors present the case of a 62-year-old male patient with an implantable cardioverter-defibrillator and end-stage heart failure supported with an intra-aortic balloon pump. Implantation of a triple-site cardiac resynchronization system and complex heart failure treatment brought a significant improvement, return to home activity and 17-month survival. The patient died due to heart failure...

The complications of chronic kidney disease (CKD) present the anaesthetist with a number of clinical challenges related in part to altered drug handling and to difficulties with vascular access and fluid balance. Safe anaesthetic management requires an understanding of CKD pathophysiology to prevent aggravation of pre-existing disease. This review will consider some recent changes in the manage...

The intricate relationship between stress and skin conditions has been documented since ancient times. Recent clinical observations also link psychological stress to the onset or aggravation of multiple skin diseases. However, the exact underlying mechanisms have only been studied and partially revealed in the past 20 years or so. In this review, the authors will discuss the recent discoveries ...

•7 of 9 patients with GGE reduced ≥ 50% their tonic-clonic seizure frequency on LCM.•All 7 patients remained seizure free for > 1 year, and 2 of them for > 5 years.•In 2 of the 9 patients, both with Juvenile Absence Epilepsy, absences aggravated.•One aggravation consisted on a myoclonia and absence status, in a patient with no history of myoclonia.•VEEG paralleled clinical improvement but didn'...

T he readers of the European Respiratory Journal are well aware of the importance of environmental exposures on the incidence and aggravation of several respiratory disorders, including asthma and chronic obstructive pulmonary disease (COPD), leading in some cases to mortality. Almost each month, one or more scientific articles deal with environmental lung diseases or with environmentally induc...

The association of chronic renal failure and anemia has been recognized since the early 19th century; nowadays such a manifestation is regarded as one of the many components of the vast array of signs and symptoms present in patients with chronic renal failure. The introduction of dialysis brought new insights to this complex subject, but also added new mechanisms for the development or aggrava...