OBJECTIVE To investigate whether age at menarche is associated with functional ovarian reserve (FOR) later in life. DESIGN Retrospective cohort study. SETTING Fertility center. PATIENT(S) Five hundred and two infertile women. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Levels of menarcheal age, antimüllerian hormone (AMH), follicle-stimulating hormone (FSH), and functional ovarian r...

The mean and median age at menarche in 360 Khasi girls was found to be 13.22 ± 0.88 and 12.13 ± 0.79 years, respectively; socio-economic status was observed to be a strong predictor of age at menarche in this population.

Larger body size in childhood is correlated with earlier age at menarche; whether birth and infant body size changes are also associated with age at menarche is less clear. The authors contacted female participants enrolled in the New York site of the US National Collaborative Perinatal Project born between 1959 and 1963 (n = 262). This racially and ethnically diverse cohort (38% white, 40% Afr...

Age at onset of menarche was determined for a group of 91 newly menstruating urban school girls in Bangladesh. Girls who had had their menarche within the last year were selected as subjects for the study. The 1-year cohort was selected so as to minimize the gap between the age at menarche and the variables of weight, height, and per capita food expenditure (PFE) to be correlated with it. Re...

Understanding the regulation of pubertal timing has relevance to developmental and human biology, and to the pathogenesis of various diseases. Recent large-scale genome-wide association studies for puberty timing and adult height, body mass index (BMI) and central body shape provide evidence for shared biological mechanisms that regulate these traits. There is substantial genetic overlap betwee...