PURPOSE Identification of all common and potentially avoidable adverse events is crucial to further improve the quality of medical care. The intention of the current study was to evaluate a standardized physician independent survey format on adverse events in total knee arthroplasty. The protocol for reporting adverse drug events following the International Conference of Harmonisation of techni...

Adverse drug events cause substantial morbidity and mortality, yet they remain underappreciated and misunderstood. The terminology to describe errors and patient harm associated with medications causes much confusion. This article uses the case study of a patient with multiple adverse drug events to clarify key terms, such as adverse event, adverse drug reaction, adverse drug event, medication ...

OBJECTIVE To calculate the absolute risk reduction of transfusion-related adverse events, the number of patients needed to treat, and cost to avoid one transfusion-related adverse event by using erythropoietin in critically ill patients DESIGN Number needed to treat with sensitivity analysis. SETTING Teaching hospital. PATIENTS Hypothetical cohort of critically ill patients who were candi...

The Adverse Event Ontology (AEO) is a realism-based biomedical ontology for adverse events. Currently AEO has 484 representational units annotated by means of terms including 369 AEO-specific terms and 115 terms from existing feeder-ontologies. In AEO, the term „adverse event‟ is used exclusively to denote pathological bodily processes that are induced by a medical intervention. This requiremen...

BACKGROUND Adverse events are poor patient outcomes caused by medical care. Their identification requires the peer-review of poor outcomes, which may be unreliable. Combining physician ratings might improve the accuracy of adverse event classification. OBJECTIVE To evaluate the variation in peer-reviewer ratings of adverse outcomes; determine the impact of this variation on estimates of revie...