Z-E Isomerisation because of rotation around the exocyclic double bond (known as the τ-twist) and not any other internal conversion has been reported to be the major nonradiative decay channel for non-hydroxylic unconstrained para and meta GFP chromophore analogues. The equation Φf + 2ΦZE = 1 has been shown to hold well for both para and meta GFP chromophore analogues. If the above equation hol...

one series of half-analogues of michler’s ketone containing one or more terminal methoxysubstituents with variable tertiary amino groups have been used in this study. nmr spectralresults for the parent ketones confirm earlier findings that ortho proton shifts are apparentlyindependent from steric effects in derivatives of michler’s ketone because the ring current andcarbonyl-induced shifts are ...

co(ii) and cu(ii) promoted base hydrolysis of 2-cyano, 1, lo-phenanthroline was studied. at 298.2°k, cu(ii) reaction is more efficient (by a factor of 20) than either co(ll) and its analogues ni(ii) in promoting base hydrolysis.

the generalization of p-frame in banach spaces is considered in this paper. the concepts of an $tilde{x}$-frame and a system conjugate to $tilde{x}$-frame were introduced. analogues of the results on the existence of conjugate system were obtained. the stability of $tilde{x}$-frame having a conjugate system is studied.

objectives in order to provide a pharmacological profile for some newly synthesized dihydropyridines, we investigated their effects on the isolated rat colon segments and the isolated rat atrium contractility. the tested compounds include alkyl ester analogues of nifedipine, in which the ortho-nitrophenyl group at position 4 is replaced by 2-alkylthio-1-benzyl-5-imidazolyl substituent, and nife...

The aim of this talk is to derive two constraints imposed by supersymmetry for a class heterotic Landau-Ginzburg models with nonholomorphic superpotentials. One these relates the parameters superpotential Hermitian curvature. Various special cases constraint have been used establish properties Mathai-Quillen form analogues which arise in corresponding models. other was not anticipated from stud...

BACKGROUND Analogues of vitamin D3 are extensively used in the treatment of various illnesses, such as osteoporosis, inflammatory skin diseases, and cancer. Functional testing of new vitamin D3 analogues and formulations for improved systemic and topical administration is supported by sensitive screening methods that allow a comparative evaluation of drug properties. As a new tool in functional...

BACKGROUND The insulin receptor (IR) exists in two isoforms, A and B, and the isoform expression pattern is tissue-specific. The C-terminus of the insulin B chain is important for receptor binding and has been shown to contact the IR just adjacent to the region where the A and B isoforms differ. The aim of this study was to investigate the importance of the C-terminus of the B chain in IR isofo...

Various ethyl and benzyl spermine analogues, including the anticancer agent N1,N12-bis(ethyl)spermine, were studied for their ability to affect the growth of cultured Escherichia coli cells, to inhibit [3H]putrescine and [3H]spermine uptake into cells, and to modulate the peptidyltransferase activity (EC 2. 3. 2. 12). Relative to other cell lines, growth of E. coli was uniquely insensitive to t...

Three new 8N-alkyl analogues of roseoflavin (MM), i.e., 8-ethylamino- (EH), 8-methylethylamino- (ME), 8-diethylamino-8-demethyl-D-riboflavin (EE), their tetraacetates, and 8-amino-8-demethyl-D-riboflavin (HH) tetraacetate, were synthesized. A relation between the anti-riboflavin activity and the chemical structure of 8N-alkyl analogues (8N-methyl, ethyl) was studied by a restoration by riboflav...