PURPOSE/OBJECTIVES To describe the experience of women with estrogen receptor-positive breast cancer who are initiating oral adjuvant therapy and to determine what they describe as facilitating and/or hindering this experience. 
. RESEARCH APPROACH Qualitative inquiry. 
. SETTING Massachusetts General Hospital Cancer Center in Boston. 
. PARTICIPANTS 14 women aged 48-81 years. 
. METHOD...

Although post-operative adjuvant chemotherapy (ACT) is only recommended for patients with stage II colon cancer who are at a high risk of recurrence, the definition of high risk remains unclear. The present study aimed to identify the risk factors for recurrence, which may also be indicators for adjuvant therapy, using a retrospective analysis of clinicopathological data obtained from stage II ...

conclusions despite the presence of vast oxidative stress in hepatitis b, antioxidant therapy is not always effective as a treatment strategy, especially considering that antioxidants can act as “double-edged swords” or antioxidants; if not used at the right time or place or in the right combination, these substances can easily become pro-oxidants. therefore, several studies will be needed to d...

Following primary treatment for early breast cancer, systemic adjuvant therapy is given to reduce the risk of recurrence by targeting any undetectable micrometastatic deposits. Adjuvant systemic treatment may include endocrine therapy, chemotherapy and antibody therapy, depending on the presence or absence of hormone receptors, HER2 status and the estimated risk of relapse. In recent years, an ...

OBJECTIVE The objective of this study is to evaluate the efficacy of adjuvant interferon therapy for hepatitis B virus-related hepatocellular carcinoma (HCC) after different previous therapy. METHODS An electronic search for articles about adjuvant treatment with IFN for patients with HCC published between 2000 and 2015 was conducted in MEDLINE, PubMed, Cochrane Library, and EMBASE databases....

INTRODUCTION Adjuvant imatinib improves recurrence-free survival of patients following resection of primary KIT-positive gastrointestinal stromal tumors. However, it is unknown whether patients who previously received adjuvant imatinib therapy will respond to imatinib rechallenge as treatment for recurrent disease. Here we present the first report documenting the benefits of imatinib rechalleng...

The prognosis of colon cancer is primarily determined through staging of the disease. After curative surgery, clinically occult micrometastases are thought to be the major source of disease recurrence. The main aim of postoperative systemic treatment is to eradicate micrometastases, thereby improving outcomes with an increased cure rate. Adjuvant systemic chemotherapy is indicated for patients ...

A systematic review of radiation therapy trials in several tumour types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for ovarian cancer is based on data from six randomized trials. Moreove...

INTRODUCTION While the standard adjuvant therapy for rectal cancer includes radiation therapy (RT) and chemotherapy (CT), the optimal treatment combination and sequencing have yet to be determined. In recent years, a large number of clinical trials have been reported in this rapidly evolving field. MATERIALS AND METHODS A review of pivotal trials in rectal cancer was undertaken with a focus o...

The effects of low-dose methylprednisolone as adjuvant therapy for hemophilia A patients with factor VIII inhibitorsSri Marwanta, Soetrisno Soetrisno, Bambang Purwanto, Brian Wasita, Tonang Dwi Ardyanto, Faizal Muhammad, Eti Poncorini Pamungkasari, Dono Indarto, Eillien Ramadhani Fauzi