One of the major clinical issues encountered after lumbar spinal fusion is the development of adjacent segment pathology (ASP) caused by increased mechanical stress at adjacent segments, and resulting in various radiographic changes and clinical symptoms. This condition may require surgical intervention. The incidence of ASP varies with both the definition and methodology adopted in individual ...

Anterior cervical fusion has become a standard of care for numerous pathologic conditions of the cervical spine. However, subsequent development of clinically significant disc disease at levels adjacent to fused discs is a serious long-term complication of this procedure. As more patients live longer after surgery, it is foreseeable that adjacent segment pathology (ASP) will develop in increasi...

1. In tuberculosis meningitis there is a tuberculosis endarteritis characterized by the formation of intimal tubercles and a diffuse subendothelial, intimal proliferation due to implantation of tubercle bacili from the blood. From the endarteritis the infiltration may spread into the muscular coat and the adventitia, and the whole wall may undergo caseous and hyaline degeneration. 2. Tuberculou...

OBJECTIVES To compare the influence of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) on adjacent segment degeneration (ASD). METHODS The study was carried out in the Traumatology and Orthopedics Laboratory, Department of Traditional Chinese Medicine, Medical School, Jinan University, Guangzhou, China, between December 2013 and November 2014. A norm...

BACKGROUND Instrumented lumbar arthrodesis has been established as the gold standard in the care of patients with degenerative disc disease. However, spinal fusion results in the elimination of motion of the functional spinal unit and has been implicated in the development of adjacent-level degeneration. Motion-preserving devices such as the dynamic rod allow for stabilization of a pathologic m...

The objective of this study was to investigate short segment decompression of degenerative lumbar scoliosis (DLS) and the efficiency of fusion treatment.After DLS surgery, the patients were retrospectively reviewed using the VAS (visual analog scale) and ODI (Oswestry Disability Index) to assess clinical outcomes. All patients underwent posterior lumbar decompressive laminectomy, pedicle screw ...

Pedicle screw instrumentation constructs have become a cornerstone in the treatment of adult spinal deformity and instability. They are known to provide greater rigidity and enhanced ability to correct and maintain spinal alignment. Biomechanical data, however, demonstrate that increased construct stiffness is associated with increased loading within adjacent segments [1– 9]. Increasingly stiff...

The purpose of this study was to prospectively evaluate the clinical and radiographic results obtained with the Bryan disc prosthesis (Medtronic Sofamor Danek, Memphis, TN) in 20 consecutive patients with single-level or two-level cervical degenerative disc disease. All patients were followed up for at least two years. The mean Neck Disability Index and the visual analogue scale for neck and ar...