Introduction: Adenotonsillar hypertrophy (AH) is considered the most common cause of upper respiratory tract obstruction among children. It results in a spectrum of symptoms from mouth breathing, nasal obstruction, hyponasal speech, snoring, and obstructive sleep apnea (OSA) to growth failure and cardiovascular morbidity. Adenotonsillectomy is a typical strategy for patients with AH, but may le...

OBJECTIVE To compare lymphocyte immunohistochemical markers and staining for Epstein-Barr virus (EBV) in tonsillectomy specimens from healthy children and pediatric transplant recipients. DESIGN Analysis of pathology specimens. SETTING Tertiary care medical center. PATIENTS Consecutive sample of tonsillectomy specimens from 60 pediatric solid organ transplant recipients and 60 healthy chi...

Vitamin D is a hormone that interacts with intranuclear receptors to effect transcriptional changes in many cell types including those in gut, bone, breast, prostate, brain, skeletal muscle, and the immune system. Inadequacy of vitamin D is widely prevalent, and leads to the classic diseases of bone demineralization as well as to more recently recognized problems such as nonspecific pain and no...

OBJECTIVE At the present time, it is generally accepted that chronic mouth breathing influences craniofacial growth and development. The objective of this study was to determine the position of the jaw, its growth direction and morphology, and the facial proportions of children with two different etiological factors of mouth breathing, at different age groups. MATERIALS AND METHODS Four group...

OBJECTIVE To describe the long-term outcome of a cohort of children with symptomatic adenotonsillar hypertrophy treated with aqueous nasal beclomethasone. METHODS The children enrolled completed a 4-week single-blind, saline solution controlled crossover study of aqueous beclomethasone (total: 400 micro g/d). In a 24-week open-label follow-on study, beclomethasone 200 micro g/d was offered to...

IMPORTANCE Evaluation of pediatric obstructive sleep apnea in resource-limited health care systems necessitates testing modalities that are accurate and more cost-effective than polysomnography. OBJECTIVE To trace the clinical pathway of children referred to our sleep laboratory for possible obstructive sleep apnea who were evaluated using nocturnal pulse oximetry and the McGill Oximetry Scor...

OBJECTIVE The transmission of the gastric pathogen Helicobacter pylori involves the oral route. Molecular techniques have allowed the detection of H. pylori DNA in samples of the oral cavity, although culture of H. pylori from these type of samples has been sporadic. Studies have tried to demonstrate the presence of H. pylori in adenotonsillar tissue, with contradictory results. Our aim was to ...

introduction: adenotonsillar hypertrophy (ah) is considered the most common cause of upper respiratory tract obstruction among children. it results in a spectrum of symptoms from mouth breathing, nasal obstruction, hyponasal speech, snoring, and obstructive sleep apnea (osa) to growth failure and cardiovascular morbidity. adenotonsillectomy is a typical strategy for patients with ah, but may le...