M F v t 65-year-old man with a history of recurrent lymphoma status-post matched sibling donor transplant presented ith swelling of the right testicle. Four years earlier, he had resented with right leg swelling, night sweats, and pelvic ain. Computed tomography (CT) scan showed bulky rightided pelvic adenopathy. Biopsy showed diffuse high-grade -cell lymphoma. The remainder of the staging eval...

BACKGROUND Disseminated mycobacterial disease is an important cause of morbidity and mortality in patients with HIV-infection. Nonspecific clinical presentation makes the diagnosis difficult and sometimes neglected. METHODS We conducted a retrospective cohort study to compare the presentation of disseminated Mycobacterial tuberculosis (MTB) and non-tuberculous Mycobacterial (NTM) disease in H...

BACKGROUND To demonstrate the diagnostic accuracy of an integrated approach of blind trans-bronchial needle aspiration (TBNA) and (99m)Tc-2-methoxy-isobutyl-isonitrile single photon emission computed tomography ((99m)Tc-MIBI-SPECT) in diagnosing mediastinal lymph adenopathy. METHODS Sixty one consecutive patients with mediastinal lymph adenopathy undergoing both TBNA and (99m)Tc-MIBI-SPECT we...

Over a 2-week period, the management of upper respiratory tract infection by 24 medical officers and medical assistants in Seremban District was studied. Each practitioner recorded clinical data and prescription for twenty consecutive patients using a structured questionnaire. The extent to which the practitioners used "predictive features" (fever, absence of cough, cervical adenopathy, enlarge...

BACKGROUND Dissection of levels II-IV as part of an elective or therapeutic neck dissection is common practice during laryngectomy for laryngeal squamous cell carcinoma (SCC). The necessity of routine dissection at level IV has recently been questioned. The purpose of this study was to find the incidence of level IV metastases in patients with transglottic and supraglottic SCC who underwent nec...

Sarcoidosis is a granulomatous disease of unknown aetiology that shows multisystemic involvement and that is predominantly seen in young and middle-aged patients, with a slightly higher prevalence in females [1]. The histological hallmark of sarcoidosis is noncaseating granulomas with proliferation of epitheloid cells [2]. Although the disorder is multisystemic, pulmonary manifestations typical...

A 22-year-old woman with no personal history came to the hospital due to fever and cervical lateral adenopathy which started 15 days prior. Laboratory tests show leukopenia 2800 per mm3 (with no lymphopenia), normocytic, normochromic anemia (hemoglobin 11 g/dl, hematocrit 34%, mean corpuscular volume 85.9, mean corpuscular hemoglobin 28.6 pg) and ESR 85 mm/h. The blood chemistry and urine sedim...

Background: To demonstrate the diagnostic accuracy of an integrated approach of blind trans-bronchial needle aspiration (TBNA) and Tc-2-methoxy-isobutyl-isonitrile single photon emission computed tomography (Tc-MIBI-SPECT) in diagnosing mediastinal lymph adenopathy. Methods: Sixty-one consecutive patients with mediastinal lymph adenopathy undergoing both TBNA and Tc-MIBI-SPECT were prospectivel...

BACKGROUND The aim is to assess the validity and reliability of transbronchial needle aspiration (TBNA) of mediastinal and hilar adenopathies and to evaluate factors predictive of TBNA outcome. METHODS We performed an analysis of prospectively collected data of patients (n = 580) who underwent TBNA (n = 685) from January 1998 to December 2007 in our center. Validity and reliability were evalu...