The study presents an experimental and numerical evaluation of bend-twist elastic coupling in composite passive-adaptive structures. Due to the lack of experimental validation in Fluid Structure Interaction (FSI) investigations, a full-field deformation of an aerofoil-shaped section under wind loading is measured. The experimental analysis is carried out at the University of Southampton 3.5 m ×...

Peptides presented by major histocompatibility complex class II (MHCII) molecules to CD4+ T cells play a central role in the initiation of adaptive immunity. This antigen presentation process is characterized by the proteolytic cleavage of foreign and self proteins, and loading of the resultant peptides onto MHCII molecules. Loading and exchange of antigenic peptides is catalyzed by a non-class...

Water quality impairment due to high mercury fish tissue concentrations and high mercury aqueous concentrations is a widespread problem in several sub-watersheds that are major sources of mercury to the San Francisco Bay. Several mercury Total Maximum Daily Load regulations are currently being developed to address this problem. Decisions about control strategies are being made despite very larg...

The physical basis of computationally tractable models of crystalline plasticity is reviewed. A statistical mechanical model of dislocation motion through forest dislocations is formulated. Following Franciosi and co-workers, the strength of the short-range obstacles introduced by the forest dislocations is allowed to depend of the mode of interaction. The kinetic equations governing dislocatio...

An ideal vaccine for induction of CD4(+) T cell responses should induce local inflammation, maturation of APC, and peptide loading of MHC class II molecules. Ligation of Toll-like receptor (TLR) 2 provides the first two of these three criteria. We have studied whether targeting of TLR2 results in loading of MHC class II molecules and enhancement of CD4(+) T cell responses. To dissociate MHC cla...

OFDM renders multipath channels with nite memory equivalent to parallel at fading subchannels, over which equalization amounts to simple phase compensation. If the channel status information is known at the transmitter side, optimal power loading across subchannels is possible. Users mobility, time and carrier asynchronism introduce variations in the equivalent channel impulse response setting ...

Recognition and elimination of virally or malignantly transformed cells are pivotal tasks of the adaptive immune system. For efficient immune detection, snapshots of the cellular proteome are presented as epitopes on major histocompatibility complex class I (MHC I) molecules for recognition by cytotoxic T cells. Knowledge about the track from the equivocal protein to the presentation of antigen...

Orthogonal frequency-division multiplexing (OFDM) with multiple transmit and multiple receive antennas (MIMO-OFDM) is considered a candidate for high-data rate communication in various existing and forthcoming system standards. To achieve the usually desired low frame and bit error rates, MIMO-OFDM should be combined with adaptive bit loading (ABL) and forward error correction (FEC) coding, whe...

Shear stress due to mechanical loading-induced flow of interstitial fluid through the lacuno-canalicular network is a likely signal for bone cell adaptive responses. Moreover, the rate (determined by frequency and magnitude) of mechanical loading determines the amount of bone formation. Whether the bone cells' response to fluid shear stress is rate dependent is unknown. Here we investigated whe...

Conductive silicone rubber has great advantages for tactile sensing applications. The electrical behavior of the elastomeric material is rate-dependent and exhibit hysteresis upon cyclic loading. Several constitutive models were developed for mechanical simulation of this material upon loading and unloading. One of the successful approaches to model the time-dependent behavior of elastomers is ...