The immune response promotes a complex series of reactions by the host in an effort to prevent ongoing tissue damage, isolate and destroy the infective organism and activate the repair processes that are necessary for restoring normal function. The homoeostatic process is known as inflammation and the early set of reactions that are induced are known as the acute phase response (APR). The APR h...

The acute phase response is traditionally characterized by hepatic synthesis of proteins as an inflammatory response to injury, with interleukin-6 (IL-6) being the key mediator. In contrast, microarray studies in human renal transplant implantation biopsies indicate a strong acute phase response in the deceased donor kidney, associated with a significant upregulation of oncostatin M receptor be...

The occurrence in the rabbit of an acute phase protein analogous to human C-reactive protein has been confirmed. The acute phase protein of the rabbit reacts with a special form of the pneumococcal somatic polysaccharide, designated Cx polysaccharide, in the same manner that the human C-reactive protein reacts with the classical C polysaccharide. The method of preparation and some of the proper...

Segregated early-weaned pigs (initially 4.0 kg and 14 +/- 1.5 d of age) were used to quantify the effects of lipopolysaccharide (LPS)-induced immune challenge and nursery diet complexity (complex, medium, and simple) on growth performance and haptoglobin production. Three treatments of immune challenge consisted of pigs given ad libitum access to feed (control), challenged with LPS and given ad...

BACKGROUND/AIM To investigate prospectively the hypothalamo-pituitary-adrenal (HPA) axis by adrenocorticotropic hormone (ACTH) stimulation test. MATERIALS AND METHODS Tularemia was diagnosed according to guidelines. An ACTH stimulation test (1 µg) and a dexamethasone suppression test (DST; 1 mg) were performed in patients in the acute phase of tularemia before antibiotic treatment and in the ...

SARS COV 2 infection causes lung lesions characterized by the appearance of ground glass opacities, and a significant percentage patients present persistent symptoms changes in CT scan represented fibrotic lesions, traction bronchiectasis, persistence images. Laser therapy has anti-inflammatory effects, stabilizes vascular endothelium, antifibrotic being useful both acute phase COV2 pneumonia, ...