Leukaemia is a cancer of blood that causes more death than any other cancers among children and young adults under the age of 20. This disease can be cured if it is detected and treated at the early stage. Based on this argument, the requirement for fast analysis of blood cells for leukaemia is of paramount importance in the healthcare industry. This paper presents the classification of White B...

Background: The present study aimed to assess the frequency of treatment related mortality (TRM) among all ALL mortalities recorded in paediatric ward. Methods: A cross-sectional was undertaken at Department Pediatric, Children’s Hospital and Institute Child Health, Multan, Pakistan between January 2021 June 2022. enrolled children under age 18 years who were diagnosed with acute lymphoblastic ...

A retrospective study of 45 patients of acute leukaemia in children (15 years age), in relation to FAB classification, is presented. Acute lymphoblastic leukaemias (ALL) were commoner than acute myeloid leukaemias (AML), with an ALL:AML ratio of 4.63:1. Amongst ALL, L1 was the most frequent type (59%), followed by L2 (35%) and L3 (5.4%), respectively. FAB types M2, M3, M4 and M5 were diagnosed ...

The purpose of any classification of leukaemia is to identify distinct biological entities which diVer in aetiology, mechanisms of leukaemogenesis, clinicopathological features, and prognosis. Since the optimal treatment for such entities diVers, their recognition is not only of scientific interest but is also essential for optimal care of patients. Acute leukaemia can be classified in many way...

BACKGROUND A previous study has suggested an increased incidence rate of leukaemia from 1978 to 1992 in people aged 0 to 24 years and living in the vicinity of the La Hague nuclear waste reprocessing plant without considering age and cytological type. SETTING The Nord Cotentin region (France) and the island of Alderney (United Kingdom). STUDY OBJECTIVE To describe the occurrence of leukaemi...

Patients with acute leukaemia have normal or near normal numbers of haemopoietic stem cells in their marrow at diagnosis. Remission is achieved when the administration of cytotoxic drugs eradicates the bulk of the leukaemic population while sparing normal haemopoiesis. The mechanism by which chemotherapy seems to act in this selective manner is essentially unknown. Nevertheless, remission rates...

BACKGROUND In 2002, a poster alerted the French health authorities to the possibility that the risk of childhood leukaemia might be increased by hepatitis B vaccination. Elucidating the role of vaccination in the aetiology of childhood acute leukaemia (AL) was therefore included in the objectives of an ongoing national study. METHODS The ESCALE study was a French national population-based cas...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Janecka A, Stefanowicz J, Owczarzak Adamkiewicz-Drożyńska E. Serum levels of salusin β in acute lymphoblastic leukaemia and Wilms’ tumour survivors – preliminary report. Pediatria Polska - Polish Journal Paediatrics. 2022;97(4):290-295. doi:10.5114/polp.2022.123915. APA Janecka, A., Stefanowicz, J., Owczarzak, & A...

case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria. BMJ 1990;300:423-9. 17 Gardner MJ. Paternal occupations of children with leukaemia. BMJ 1992;305: 715. 18 Beral V. Leukaemia and nuclear installations. BMJ 1990;300:41 1-2. 19 McLaughlin JR, Anderson TW, Clarke EA, King W. Occupational exposure of fathers to ionizing radiation and the ...