The cytotoxic effect of peripheral lymphocytes on chicken red blood cells (ChRBC) coated with purified hepatitis B surface antigen (HBsAg) has been studied as an in vitro parameter of cell-mediated immunity in acute and chronic infection with hepatitis B virus. Using this technique, the mean cytotoxic index of lymphocytes from patients with acute hepatitis B (29.13 +/- 20.88) was significantly ...

Laboratory diagnosis of acute infection of hepatitis E virus (HEV) is commonly based on the detection of HEV RNA, IgM and/or rising IgG levels. However, the profile of these markers when the patients present have not been well determined. To clarify the extent of misdiagnosed sporadic hepatitis E in the initial laboratory detection, serial sera of 271 sporadic acute hepatitis cases were collect...

Immunoglobulin M (IgM) antibodies against hepatitis B core antigen (anti-HBc) and hepatitis A virus (anti-HAV) were determined in 41 cases of acute viral hepatitis. In sera positive for anti-HBc or anti-HAV, IgM was separated from IgG by reorienting sucrose gradient high-speed centrifugation, and the IgG- and IgM-containing serum fractions were tested for the presence of specific antibody by ra...

BACKGROUND AND OBJECTIVES The aim of this study was to estimate the proportion of spontaneous viral clearance (SVC) after symptomatic acute hepatitis C and to evaluate the efficacy of 12 weeks of pegylated interferon alfa-2a in patients who did not clear the virus spontaneously. METHODS Patients with symptomatic acute hepatitis C were recruited from two "fever hospitals" in Cairo, Egypt. Pati...

Objectives & background: Drug-induced hepatotoxicity (DIH) is a common side effect of anti-TB drugs. Acute viral hepatitis (AVH) may be confounded with chronic alcoholic clinically, biochemically, and histologically (CAH). Place Study: Rashid Latif Medical College Lahore Duration March 2019 to January 2021 Methods: This prospective research examined the acute as contributing confounding fac...

Pediatric acute liver failure (PALF) has recently become a subject of great interest when multiple clusters non-A to non-E severe hepatitis in otherwise healthy young children with median age 2 years were reported around the world [...]

Since Indonesia is a huge archipelago country, the prevalence of hepatitis virus infection highly varies among islands. In average the prevalence of clinical hepatitis in Indonesia was 0.6% in the year 2007. Of 82 clinical acute hepatitis patients treated in hospitals in several cities, acute hepatitis A accounted for 28.0%, acute hepatitis B 13.4%, and acute hepatitis C 1.2%; 35.4% patients we...

one of the most serious kinds of hepatitis is hepatitis b. this condition is more common than aids, and is 100 time more contagious. in iran the most common cause of acute and chronic hepatitis, liver cirrhosis, and also hepatocellar carcinoma in adults, is hepatitis b. more than two billion people are infected and more than 350 million of individuals are carriers of this virus in the entire wo...

With advances in tools for the diagnosis of hepatitis C virus (HCV) infection, it has become easier to evaluate the natural course of hepatitis C. Although HCV infection initially occurs in adult individuals, in most patients with acute hepatitis C (68%) it develops into chronic hepatitis. Once chronic hepatitis is established, the rate of spontaneous cure of the liver disease is very rare (bel...