Objective: Homalium letestui Pellegr (Flacourtiaceae) is used in traditional medicine in parts of Nigeria for the treatment of malaria, ulcer, and inflammatory diseases and as an aphrodisiac. This investigation was aimed to evaluate the cytotoxic, immunomodulatory, and antileishmanial properties of stem extract and fractions of Homalium letestui (H. letestui). Materials and Methods: Cytotoxic a...

Introduction: There is a strong relationship between infectivity with Human Immunodeficiency Virus (HIV) and Herpes Simplex Virus (HSV); however the process leading to chronic herpetic lesions in HIV is still under investigation. Case report: There is evidence that patients receiving highly active antiretroviral therapy (HAART) may be more prone to chronic ulcers than those not receiving therap...

Patients 182 patients (68% women) who were 18–74 years of age and had Crohn’s disease confined to the distal ileum, ileocaecal region, and ascending colon which was confirmed by colonoscopy, small bowel follow through, or barium enema in the previous 24 months. Exclusion criteria were Crohn’s disease in the rectum; septic complications; abscess; perforation; active fistulas; ileostomy; colostom...

Extract of gazyagi has protective effect against ethanol-induced gastric ulcer and it decreases microscopical ulcer index in rat. At the last some years, treatment of peptic ulcer by medicinal herbs have been were very successful. Gazayagi (Falcaria vulgaris) is a member of Umbelliferae family. In the folk medicines of the west of country, this herb is used for healing of skin ulcer and peptic ...

  Background and Objective: Long period risk of gastric carcinoma in people affected with chronic Helicobacter pylori gastritis is 5 times more than normal people. Perhaps histological changes due to helicobacter pylori infection could be used for screening people at risk of gastric carcinoma and peptic ulcer. Materials and Methods: This study has been carried out as a cross...

THE lumen of the first part of the duodenum is a comparatively narrow segment of the alimentary canal so that when the surgeon passes his finger along its length at operation he finds that its mucosa hugs him comfortably. Placing an ulcer into this canal and surrounding its crater by scar tissue would, one might think, produce stenosis in a high percentage of cases, yet the somewhat surprising ...

Ninety patients with duodenal ulcer, divided randomly into three groups, were treated continuously for one year with either glycopyrronium, 1-hyoscyamine (as a sustained-release preparation) or inert tablets. Dosage with active tablets was so adjusted that the patient experienced definite but tolerable side-effects. Basal and maximal gastric acid secretion were measured immediately before and o...

BACKGROUND Venous leg ulcers are common, troublesome, and their failure to heal is often related to a heavy bio-burden. Ionized silver has both anti-inflammatory and antimicrobial properties. The ulcer healing properties of the silver releasing foam dressing Biatain Ag has been examined in 4 randomized controlled trials (RCTs). AIM To evaluate ulcer healing through a meta-analytic approach af...

BACKGROUND AND AIMS The genetic trait plays a part in the pathogenesis of peptic ulcer disease. To identify a DNA marker for peptic ulcer disease, the association between the restriction fragment length polymorphism (RFLP) of the pepsinogen C (PGC) gene and peptic ulcer disease was investigated. PATIENTS AND METHODS One hundred and seventy seven unrelated controls, 75 patients with gastric ul...