-5-Phenoxysulphonyl-l-methyl-4-nitroimidazole (NSC 38087) can act as a sensitizer of hypoxic mammalian cells to radiation in vitro. The degree of sensitization achieved is greater than would be predicted from the drug's electron affinity. Cytotoxicity studies have shown that 5pM NSC 38087 can reduce the surviving fraction of log-phase V79 cells in air at 37°C to 10-2 after 2 h exposure. This to...

1,4-Dihydropyridines (1,4-DHPs) are recognized as one of the most versatile pharmacophores present as central core in many pharmaceuticals. Low yield and harsh reaction conditions prompted the researchers for the development of new environmental- friendly methods for the synthesis of 1,4-DHPs. This review explored the development of various green chemistry approaches using new catalysts develop...

despite several authors having studied the strategic approach to environmental orientation and,considering that environmental proactivity is emerging in business strategy, it still remains unclear which realactions influence a firm’s environmental orientation. an empirical analysis of a sample of 126 spanish companies shows that firms’ actions are explained as training, information and divulgat...

this paper describes a new method for the evaluation of non-utility generation impacts on preventive-corrective control of power systems. the proposed method relies on a mixed integer nonlinear optimization and is capable of recognizing the effectiveness of demand side preventive-corrective actions. a number of cases are presented to illustrate the consequences of introducing demand side action...

conclusions according to the findings, there has been a rise in the number of unsafe actions in machinery and maintenance service units compared to other maintenance units. as such, training courses based on the behavior-based safety principles at the beginning of employment, close monitoring of health safety environment (hse) officials on the implementation of regulations, and provision of app...