نتایج جستجو برای: actinomycin d

تعداد نتایج: 577953  

Journal: :Biotechnology & Biotechnological Equipment 2009

2013
Changmin Chen Diane R. Wonsey Madeleine E. Lemieux Andrew L. Kung

Fusion of the EWS gene to FLI1 produces a fusion oncoprotein that drives an aberrant gene expression program responsible for the development of Ewing sarcoma. We used a homogenous proximity assay to screen for compounds that disrupt the binding of EWS-FLI1 to its cognate DNA targets. A number of DNA-binding chemotherapeutic agents were found to non-specifically disrupt protein binding to DNA. I...

Journal: :Antimicrobial agents and chemotherapy 1976
J T Powell J H Bond

Minimal inhibitory concentration (MIC) values for penicillin G, tetracycline, amoxicillin, and actinomycin D were determined for 81 strains of Neisseria gonorrhoeae isolated from patients attending public health clinics in the Piedmont region of South Carolina. Gonococcal isolates were also screened for highlevel resistance to streptomycin. Significant positive correlations (r >/= 0.45, P </= 0...

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