The tubulin polymerization and Src kinase signaling inhibitor tirbanibulin is being investigated as a topical treatment for actinic keratosis, precursor of squamous-cell carcinoma.

This study aims to develop and validate an investigator global assessment score (IGA) for keratosis pilaris (KP), a highly prevalent, benign, follicular disorder, standardize disease assessment. To our knowledge, there is currently no scoring system KP. A composite IGA score, Keratosis Pilaris Area Index (KPAI), was created compared 0-4 defined KP known as KP-IGA. validation done determine the ...

Dermatofibroma is a frequent benign tumor of easy clinical diagnosis in most cases, but that can mimic other dermatoses. Dermoscopy may help to define the diagnosis and its classical pattern is a central white area, similar to a scar, surrounded by a discrete pigment network. However, dermoscopic findings are not always typical. We describe here a case of dermatofibroma exhibiting ridges, furro...

This paper describes the participation of Araguaia Medical Vision Lab at the International Skin Imaging Collaboration 2017 Skin Lesion Challenge. We describe the use of deep convolutional neural networks in attempt to classify images of Melanoma and Seborrheic Keratosis lesions. With use of finetuned GoogleNet and AlexNet we attained results of 0.950 and 0.846 AUC on Seborrheic Keratosis and Me...

neous biopsies, yielding 69 collision tumors. Cascajo and colleagues found 54 collision tumors of malignant cutaneous neoplasms associated with seborrheic keratoses in 85,000 biopsies. The most common combinations found by Boyd and Rapini included basal cell carcinoma and nevus (14), basal cell carcinoma and seborrheic keratosis (8), nevus and seborrheic keratosis (14), actinic keratosis and ne...

Introduction: Keratosis pilaris(KP) is a disorder of keratinization of hair follicles characterized by keratin plugs in the hair follicles with perifollicular erythema.It may be inherited with X-Linked Dominant, or may be sporadic. Aim of the study: to compare the efficacy of 30% Salicylic acid and Long pulsed 1064nm Nd:YAG laser for treatment of keratosis pilaris. Materials and methods: Out of...

Actinic keratoses are encountered by physicians worldwide on a daily basis. As these precancerous lesions can transform to skin carcinomas, it is important to understand the many available options to use as treatment. In recent years, new therapeutic options have emerged to treat this common condition. These treatments as well as a review of the literature of conventional therapies will be disc...

OBJECTIVE To compare three methods of guideline development, to see whether using alternative evidence-based methods resulted in variation of recommendations for treating actinic keratosis. METHODS Method 1 followed a standard multiple session evidence-based approach with a working group. In method 2 recommendations were formulated by a working group during a 2-day conference. Method 3 used o...