Organic solvents are constantly present in the pharmaceutical production processes. They are usually used at any step of the synthesis pathway during the drug product formulation process. Organic solvents play an important role in the pharmaceutical industry, and appropriate selection of the solvents for the synthesis of drug substance may enhance the yield, or determine characteristics such as...

This Special Issue, entitled “Advances in deep eutectic solvents: New green solvents”, was organized to collect original research articles on the latest developments new solvents, solvents (DESs), and their applications [...]

Switchable solvents are changing properties when exposed to an external stimulus. As example, for thermomorphic multiphasic system (TMS), temperature changes can induce phase separations. Aqueous systems presented here formulated with a carboxylic acid (weak acid) and amphiphilic tertiary amine base). They show thermo-switchable hydrophobicity after separation, the weak base mainly found in org...