piroxicam (px), an anti-inflammatory drug, exhibits poor water solubility, dissolution and flow properties. thus, the aim of the present study was to improve the solubility and dissolution rate of px by freeze drying technique using dimethylformamide (dmf), chloroform and water as co-solvent system. the prepared crystals containing px were evaluated for dmf and chloroform solvent residual by ga...

The solubility of calf thymus chromatin and chromatin depleted of F1-histone has been examined under various conditions in sodium chloride. F1-depleted DNH was more soluble than native DNH at low concentrations but this difference became small at high concentrations (1mg/ml). Both exhibited minimum solubility in 0.15M -NaCl. The effect of pH and of maleylation of the mino acid side chains on th...

The influence of co-overexpression of the bacterial chaperonins GroEL and GroES on solubility, tetramer formation and enzyme activity of three variants of heterologously-expressed human medium-chain acyl-CoA dehydrogenase (MCAD) was analysed in order to investigate the molecular mechanism underlying MCAD deficiency caused by the prevalent K304E mutation. Depending on which of the three amino ac...

Cholic acid, deoxycholic acid, chenodeoxycholic acid, and ursodeoxycholic acid were purified by a foam fractionation method. Using thermogravimetric analysis, the attached water molecule was found to be completely removed from solids of the latter three at 100°C, while cholic acid still had one water molecule of crystallization per two cholic acid molecules at that temperature. The acidity cons...

Silver containing nanocomposites receive increasing attention as antibacterial coatings. In this study we report on production of such materials using combination of gas aggregation sources of Ag nanoparticles and plasma enhanced chemical vapour deposition performed in HMDSO/O2 working gas mixtures. The main attention is devoted to the investigation of solubility of Ag nanoparticles in water in...

The solubility and the stability of curcumin increases to a significant extent in the solution containing lactic acid. There was two fold increase in the solubility in 60% lactic acid at a pH 7.0 and twenty fold increase at pH 1.5 when compared to aqueous solution at pH 7.0. Almost similar increase in half life was observed. The (t1/2) of aqueous solution, at pH 7.0, was 5.7 hr., In the presenc...

Stearic acid was incorporated into whey protein through emulsification to produce films. Whey protein films were prepared by dispersing 6.5% protein in distilled water. Glycerol was the plasticizer agent. Stearic acid was added at different levels (0.0 to 1.0%) and the films were analyzed at different pHs (5.0, 6.0, 7.0 and 9.0). The emulsion films were evaluated for mechanical properties, wate...

the catalytic oxidation of toluene to benzoic acid in the liquid phase has been studied in an un-stirred tank reactor. low concentration of acetic acid was added in order to increase the solubility of the catalyst in toluene. the dependence of the rate of reaction on the concentration of toluene catalyst and oxygen pressure was studied. it has been suggested that liquid phase oxidation of tolue...

The toxic action of cadmium in the bone tissue is known, but its mechanisms are still unexplained. We examined whether Cd influences collagen content and its solubility in the femoral bone of three-week-old female rats exposed to 5 or 50 mg Cd/l in drinking water. Non-cross linked collagen was extracted with 0.5 M acetic acid, and two acid-insoluble collagen fractions were extracted with pepsin...

The Oil & Gas Journal, in 2004, states that CO2 flooding is the fastest-growing enhanced oil recovery technique in USA, and production derived from CO2 projects has more than tripled from 50,000-Barrels/day to 200,000-Barrels/day. Cyclic injection of CO2 and N2 combines environmental benefits attendant to reducing CO2 concentrations in the atmosphere and economic benefits realized through impro...