A novel class of planar, highly conjugated all-carbon macrocycles, which we christened "radiaannulenes", have been prepared based on acetylenic scaffolding using tetraethynylethene (TEE) building blocks; these structures are powerful electron acceptors and, upon peripheral substitution with electron-donating N,N-dialkylanilino groups, display intense intramolecular charge-transfer.

Substituted pyrroles were prepared by a gold(I)-catalyzed acetylenic Schmidt reaction of homopropargyl azides. The reaction allows for regiospecific substitution at each position of the pyrrole ring under mild conditions. A mechanism in which azides serve as nucleophiles toward gold(I)-activated alkynes with subsequent gold(I)-aided expulsion of dinitrogen is proposed.

an efficient three-component reaction of dialkyl acetylendicarboxylates and 2-pyrrolidin in the presence of triphenylphosphine produces dialkyl 2-(2-pyrrolidin-n-yl)-3-(triphenylphosphanylidene)succinate. these phosphoranes undergo mild intramolecular wittig reaction to produce dialkyl (e)-2-(4,5-dihydro-3h-pyrrol-2-yl)fumarate in excellent yields.

Multicomponent reactions involving azines (4-methylpyridine, isoquinoline and N-methyl imidazole) and acetylenic ester were undertaken in the presence of CH compound such as 2-furoyl trifluoroacetone(4,4,4-trifluoro-1-thiophen-2-yl-butan-1,3-dione) to generate enaminoesters as stable 1,4-diionic compounds in high yields.

Deprotection of phosphate, phosphate, and sulfite esters by silica chloride is described. Silica chloride is a mild, selective, and effective reagent for cleavage of benzyl and t-butyl esters of the above compounds.

deprotection of phosphate, phosphate, and sulfite esters by silica chloride is described. silica chloride is a mild, selective, and effective reagent for cleavage of benzyl and t-butyl esters of the above compounds.

A general, mild and efficient protocol has been developed for the synthesis of esters and thioesters. The process has been taking place using tetra n-butylammonium iodide (TBAI) as a phase-transfer catalyst and in the presence of potassium carbonate (K2CO3). A wide range of esters and thioesters was prepared in high yields and suitable times by the treatment of alcohols, phenols and thiols with...