The localization and some characteristics of mouse adrenal C19-steroid 5fi-reductase were determined by the incubation of subcellular fractions of mouse adrenal tissue with [7a-3H]androst-4-ene-3,17-dione. This enzyme was present only in the soluble fraction and was NADPH-dependent, although a small activity in the presence ofNADH was also detected. The soluble fraction also contained 3 a-, 3,6...

An inferred ancient episode of heating and deformation on Tethys has been attributed to its passage through a 3:2 resonance with Dione (Chen, E.M.A., Nimmo, F. [2008]. Geophys. Res. Lett. 35, 19203). The satellites encounter, and are trapped into, the e-Dione resonance before reaching the e-Tethys resonance, limiting the degree to which Tethys is tidally heated. However, for an initial Dione ec...

Two novel Sb(III) and Sb(V) peri-substituted acenaphthene phosphorus−antimony compounds were prepared. The compound, 1, was prepared via reacting the organolithium precursor with dichloro(p-tolyl)Stibine, 2 by chlorination of 1. Both 1 characterized multinuclear (1H, 13C 31P) NMR spectroscopy, their molecular structures resolved single-crystal X-ray diffraction. show a dative P−Sb interaction a...

Syntheses of heteroleptic 1,8-bis(phosphino)naphthalenes and 5,6-bis(phosphino)acenaphthenes were attempted using several synthetic strategies. Reaction of aryllithium with triphenylphosphite gave ArP(OPh)(2) (Ar = substituted naphthalene or acenaphthene), which was transformed into ArP(CF(3))(2), using a nucleophilic trifluoromethylation reaction with Me(3)SiCF(3)/CsF. The importance of the co...

3-Ketosteroid-∆1-dehydrogenase (KstD), a key enzyme in microbial steroid catabolism, catalyzes the trans-axial elimination of the C1 and C2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids, and it was usually used to transform androst-4-ene-3,17-dione (AD) to produce androsta-1,4-diene-3,17-dione. Here, the KstD from Gordonia neofelifaecis was expressed efficien...

A method capable of determining 13 PAHs (acenaphthene, anthracene, benzo[a]anthracene, benzo[a]pyrene, benzo[b]fluoranthene, benzo[k]fluoranthene, chrysene, dibenzo[ah]anthracene, fluoranthene, fluorene, indene[1,2,3-cd]pyrene, phenanthrene and pyrene) in a mixture of 16 EPA PAHs by second derivative synchronous spectrofluorometry in the constant wavelength mode was developed. It has not been p...

The level and source of 16 polycyclic aromatic hydrocarbons (PAHs) were investigated in the surface sediments from the Gorgan Bay, Caspian Sea. The sum of 16 PAHs (ΣPAH16) concentrations varied from 107.87 to 516.18 ng g(-1)dry weight, with average value of 270.96 ± 150.47 ng g(-1)dry weight. Ecological risk assessment of PAHs, indicated that adverse biological effects caused by acenaphthene, n...

The lipophilicity of a series of Schiff base ligands and their complexes with nickel(II) and copper(II) has been determined by reversed-phase thin-layer chromatography using binary dioxane-water mobile phase. Chelate ligands were prepared by condensation of diamine and the corresponding beta-diketone. Copper(II) and nickel(II) complexes with chelate ligands containing ethane-1,2-diamine or prop...