Zygomycetes cause serious invasive infections, predominantly in immunocompromised and diabetic patients with poor prognoses and limited therapeutic options. We compared the antifungal function of human polymorphonuclear leukocytes (PMNLs) against hyphae of Rhizopus oryzae and R. microsporus, the most frequently isolated zygomycetes, with that against the less frequently isolated Absidia corymbi...

Introduction Rhinocerebral mucormycosis is a rare life-threatening infection caused by fungi from the family of mucoraceae. Here we report a rare case of Rhinocerebral mucormycosis in a 67-year-old diabetic patient. Case Report A previously healthy 67-year-old male presented with swelling and pain over the left side of the face, deviation of the angle of the mouth to right side and drooling of ...

Serum precipitins have a controversial diagnostic value in hypersensitivity pneumonitis (HP). The present authors' objective was to assess their diagnostic value by developing scores from a panel of specific antigens tested by two techniques (electrosyneresis and double diffusion) to discriminate active HP from other interstitial lung diseases. Consecutive patients presenting with a condition f...

The synthesis of different classes of prenylated aglycones (α,β-dihydroxanthohumol (2) and (Z)-6,4'-dihydroxy-4-methoxy-7-prenylaurone (3)) was performed in one step reactions from xanthohumol (1)-major prenylated chalcone naturally occurring in hops. Obtained flavonoids (2-3) and xanthohumol (1) were used as substrates for regioselective fungal glycosylation catalyzed by two Absidia species an...

2008 Introduction Several members of the class Zygomycetes have been reported as agents of opportunistic fungal infections designated as zygomycoses. They can cause severe and frequently fatal infections in debilitated or immunocompromised patients. Rhizopus, Mucor, Absidia and Rhizomucor species seem to be most frequently involved in human and animal mycotic diseases. The risk of development o...

Saprophytic and corprophilous fungal flora on dung samples of different hybrid cow in Lawspet area of puducherry, India was studied by moist chamber method during 2014-15. During the isolation and identification of fungi from hybrid cow dung samples, 16 species under 7 genera of hyphomycetous fungi were isolated with 44 isolates from the dung samples. Aspergilli and penicilli were dominated amo...

Chemical fungicides viz. propiconazole, thiram, bayleton, copper-oxy-chloride, benomyl and mancozeb in three different concentrations were screened for their fungicidal efficacy against P. pinnata seed mycoflora viz., Penicillium sp., A. oryzae, A. ustus, A. sydowii, A. fumigatus, A. flavus, A. niger, Rhizopus sp., Fusarium sp., C. gloeosporioides and Absidia sp. in in-vitro conditions by poiso...

BACKGROUND AND OBJECTIVES Mucormycoses are seen with an increasing incidence in immunocompromised patients. Most common presentations are rhinocerebral and pulmonary. We here report the experience of a single center with mucormycoses in patients with hematologic malignancies. RESULTS Mucormycoses were diagnosed in six patients, (median age of 52 years; range, 26-74) treated between 2001-2004....

Fungal pure cultures identified with both classical morphological methods and through barcoding sequences are a basic requirement for reliable reference sequences in public databases. Improved techniques for an accelerated DNA barcode reference library construction will result in considerably improved sequence databases covering a wider taxonomic range. Fast, cheap, and reliable methods for obt...