PURPOSE To investigate the relationship between spectral domain optical coherence tomography (SD-OCT) findings and visual outcomes following resolution of macular edema in central retinal vein occlusion (CRVO). METHODS Patients with recent onset CRVO who had undergone SD-OCT and fluorescein angiography (FA) exams on the day of initial presentation were included. All patients had resolution of...

Purpose: To assess the association between the features of optical coherence tomography (OCT) and fluorescein angiography (FA) in clinically significant diabetic macular edema. Materials and Methods: It was an observational, cross-sectional study conducted at Upgraded Department of Ophthalmology, S.M.S Hospital and Medical College, Jaipur. It involved 181 eyes (100 patients) with clinically sig...

PURPOSE To describe the fundus autofluorescence (FAF) features of the inflammatory maculopathies and develop a quantification method for FAF analysis. METHODS This is a retrospective, consecutive case series of patients with inflammatory maculopathies from two tertiary centers. The clinical findings, demographics, and FAF imaging characteristics were reviewed. Foveal autofluorescence (AF) was...

A patient with macular edema secondary to a branch retinal vein occlusion (BRVO) was treated with intravenous injections of infliximab, an antitumor necrosis factor (TNF)-alpha antibody, for her rheumatoid arthritis (RA). Before the injection, the thickness of the right fovea, determined by optical coherent tomography, was 629 mum and the best-corrected visual acuity (BCVA) was 20/50. After eig...

PURPOSE To examine whether genetic factors significantly influence macular thickness in healthy older subjects. METHODS A classic twin study was performed to compare the correlation of macular thickness between monozygotic (MZ) and dizygotic (DZ) twins in a sample of population-based volunteer twins. The study included 109 white twin pairs from 50 to 80 years of age without evidence of manife...

Acute Macular Neuro-retinopathy (AMN) is a rare clinical entity. We present case of 26 years old male who presented with one-week history sudden onset decrease vision in left eye associated paracentral scotomas. Dilated fundus examination the showed multiple reddish brownish petalloid para-foveal lesions apex pointing toward fovea. OCT hyper-reflective bands Outer Nuclear Layer and Plexiform al...

PURPOSE Vascular endothelial growth factor (VEGF) concentrations in various regions of the vitreous were examined in patients with diabetic macular edema (DME) to explore the possibility of a concentration gradient in the vitreous. METHODS Vitreous samples were collected during vitrectomy from 71 eyes of 71 patients with DME and without posterior vitreous detachment who had not undergone panr...

PURPOSE To investigate 12-month treatment outcomes of anti-vascular endothelial growth factor therapy in eyes with typical exudative age-related macular degeneration with good baseline visual acuity. METHODS This retrospective observational case series included 18 eyes (18 patients) with typical exudative age-related macular degeneration with a baseline best-corrected visual acuity of 20 / 25...

Background & Aims: Alopecia areata is a chronic inflammatory disorder that affects the hair follicles. The condition most commonly presents with the sudden appearance of non-scarring discrete patches of alopecia on the scalp. Due to being an autoimmune disease, alopecia areata is observed in concomitantly with other diseases. In some studies, ocular alterations were surveyed in these patients. ...

PURPOSE To measure, using the retinal thickness analyzer, the mean foveal thickness and the mean perifoveal thickness values on patients suffering from mild non-proliferative diabetic retinopathy without clinically detectable macular edema (classified by the ETDRS study), and compare them with healthy individuals. METHODS Observational analytical retrospective case-controlled study, on a samp...