Four new steroid saponins 1-4 were isolated from the rhizomes of Anemarrhena asphodeloides (Asparagaceae), as well as four known saponins: anemarsaponin B (5) timosaponin D (6), timosaponin E1 (7) anemarsaponin B II (8). Their structures were established through UV and NMR as well as MS data. All the compounds were evaluated for cytotoxicity against HepG2 and SGC7901 human cancer lines. Compoun...

A new steroidal saponin, named pumilum A (1), and a new phenolic glycoside, threo-1-(4'-hydroxy-2'-methoxyphenyl)-2-(2",4"-dihydroxyphenyl)-1,3-propanediol-4'-O-β-D-glucopyranoside (7) were isolated from the methanolic extract of the bulbs of Lilium pumilum DC, along with five known steroidal saponins. Their chemical structures were elucidated on the basis of detailed spectroscopic analysis, in...

A new steroidal saponin was isolated from the leaves of Agave shrevei Gentry. Its structure was established as 26-(beta-D-glucopyranosyloxy)-22-methoxy-3-(O-beta-D-glucopyranosyl-(1-->2)O-[O-beta-D-glucopyranosyl-(1-->4)-O-[O-beta-D-glucopyranosyl-(1-->6)]-O-beta-D-glucopyranosyl(1-->4)-beta-D-galactopyranosyl]oxy)-(3beta,5alpha,25R)-furostane. The structural identification was performed using ...

What does Islam have to offer health-care ethics that cannot be found elsewhere? I do not mean to suggest that there is only one answer to this question, because there are many. However, I will focus on the elevated status of the patient as the recipient of compassionate care. Today, the primary medical ethical issue is no longer a quandary such as “Should we withdraw artificial nutrition and h...

The ginseng plant (Panax ginseng Meyer) has a large number of active ingredients including steroidal saponins with a dammarane skeleton as well as protopanaxadiol and protopanaxatriol, commonly known as ginsenosides, which have antioxidant, anticancer, antidiabetic, anti-adipocyte, and sexual enhancing effects. Though several discoveries have demonstrated that ginseng saponins (ginsenosides) as...

The side chain of a compound plays an important role in its biological function. In our studies, we have found that hydroximinosteroid derivatives with different side chains and position of hydroximino on ring A and B displayed remarkable distinct cytotoxicities against a diversity of cancer cell types. Presence of an oxime group on ring B and a hydroxy on ring A or B resulted in a higher cytot...

Asparagus racemosus is an herbaceous perennial plant. It is the most important rasayana herb in Ayurvedic medicine which grows in low forest areas throughout India. Their medicinal usages have been reported in indigenous systems of medicine, Indian and British Pharmacopoeias. In Ayurveda, A. racemosus has been used extensively as an adaptogen to increase the non-specific resistance of organisms...

CONTEXT Despite advances related to the provision of emergency contraception in Canada, particularly the granting of independent prescriptive authority to pharmacists in 2000, little is known about the ways in which women perceive potential barriers to using it. METHODS In 2004, an ethnically diverse sample of 52 women living in Greater Vancouver participated in interviews that were analyzed ...

AIMS to compare the benefits and harms of misoprostol to induce labour in the second and third trimester of pregnancy with cervagem. METHODS MEDLINE was searched using the terms abortion, induced; abortifacient agents; pregnancy, second trimester; pregnancy, third trimester; misoprostol; cervagem; and gemeprost to identify randomised controlled trials in which misoprostol was compared with ce...

Dalbergia latifolia commonly known as bilayatti shisham (Fabaceae) is a medicinal plant. The dry bark is brown coloured astringent characters. Traditionally various species are reported to be used as aphrodisiac, abortifacient, expectorant, anthelmentic, antipyretic, appetizer, allays thirst, vomiting, burning sensation, cures skin diseases, ulcers Ayurvedic practice, bark is used as leucoderma...