BACKGROUND & OBJECTIVE Bihar State of India has been an endemic State for kala-azar. There has been many phases of DDT sprays for vector control. An outbreak of kala-azar occurred in Goanpura, 6 km from Patna, Bihar, in 2003. We undertook this study with a new approach of kala-azar elimination in this village with priority to treatment of cases followed by supplementation with supervised DDT sp...

1. Khod AS, Thompson MH. Visceral leishmaniasis contracted in the Mediterranean area. Arch Dis Child 1983; 58 : 930-931. 2. Manson Bahr PEC, A,pted FLC. Manson's Tropical Diseases. 18th edition. London : Balliare Tindall. 1982 : 93-104. 3. Cachia EA, Fenech FF. A review of kalaazar in Malta from 1947 to 1962. Trans R Soc Trop Med Hyg 1964; 58 : 234-241. 4. Ozsoylu S, Hicsonmez G. Mediterranean ...

This is a randomized hospital-based study of fifty cases from either sex-all above the age of twelve years. There were 41 (82%) male and 9 (18%) female patients. 52% of cases belong to low income group and 48% hail from middle class. Occupations of the patients were cultivation (26%), service (24%), studentship (20%), housewife (i 4%) and business (10%). The study shows malignant disorders of h...

OBJECTIVE To compare the outcome of treatment of Sudanese kala-azar patients treated under field conditions with either branded sodium stibogluconate (SSG) (Pentostam GlaxoWellcome) or generic SSG (Albert David Ltd, Calcutta, supplied by International Dispensary Association, Amsterdam). METHOD Randomised comparison. 271 patients were treated with Pentostam and 245 with generic SSG. RESULTS ...

OBJECTIVE To compare the use of generic and proprietary sodium stibogluconate for the treatment of visceral leishmaniasis (kala-azar). METHODS A total of 102 patients with confirmed kala-azar were treated in a mission hospital in West Pokot region, Kenya, with sodium stibogluconate (20 mg/kg/day for 30 days)--either as Pentostam (PSM) or generic sodium stibogluconate (SSG); 51 patients were a...

an attempt to see when these properties attain their normal values during the course of treatment of kala-azar patients, it was found that even after a period of two months after the courses of injections are finished, the serum does not attain its normal value so far as these physical properties are concerned. Simultaneously with these experiments, Napier's aldehyde reaction has also been foll...

Bihar, India has been in the grip of kala-azar for many years. Its rampant and severe spread has made life miserable in most parts of the state. Such conditions require a comprehensive understanding of this affliction. The numbers coming out of the districts prone to the disease in the north and south Ganges have provided us with several startling revelations, as there are striking uniformities...

mammalian hosts (9). Drug resistance or sensitivity is based on sequences of M2 and NA. Substitution within residues including L26I, V27A/I, A30S, and S31N of the M2 ion channel protein was used to predict amantadine-resistant mutants, and H274Y of the NA was used to predict for oseltamivir resistance (10). The virus observed in 2006 isolates from Phichit was resistant to amantadine but sensiti...