background: radioprotective capability of histamine h2 receptor antagonists have been shown in several in vivo studies mainly using animal models. however, to verify the effectiveness of these agents in clinical applications, studies should be performed on human cells. in the present study radioprotective properties of these agents was examined in vitro on human lymphocytes using metaphase anal...

The development of a metasurface lens, which represents flat optical element with subwavelength thickness, holds the potential for miniaturizing imaging systems. Nevertheless, presence aberrations poses significant challenge achieving optimal quality out it. Moreover, its practical utilization in cameras and wearable devices necessitates simultaneous correction monochromatic chromatic aberratio...

An influence model of collimating lens aberrations in an autocollimation system based on the ray-tracing method is established. With method, this can accurately compute direction and position each light ray passing through system, thereby obtaining light-spot sensor determining systematic error caused by aberrations. Eventually, serves to compensate for measurement autocollimators improve accur...

This study aimed to investigate the effects of femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE) on higher-order aberrations in patients. 56 cases (112 eyes) undergoing refractive surgery in our hospital were selected in this study, all patients were randomly divided into femtosecond laser-assisted in situ keratomileusis group (LASIK gr...

BACKGROUND There is still an open question how to predict colorectal cancer risk before any morphological changes appear in the colon. OBJECTIVE The purpose was to investigate aberrations in chromosomes 1, 2 and 4 in peripheral blood lymphocytes analyzed by fluorescence in situ hybridization technique as a tool to assess the likelihood of colorectal cancer. METHODS A hospital-based case-con...

Both the anterior surface of the cornea and the internal optics (the posterior cornea, crystalline lens) contribute to the aberration of a wavefront passing through the eye. Artal, Guirao, Berrio, and Williams (2001) reported that the wavefront aberrations produced by the internal optics offset, or compensate for, the aberrations produced by the cornea to reduce ocular wavefront aberrations. We...

In a previous epidemiological study on acute myelocytic leukemia (M. M. Crane et al., Cancer Epidemiol. Biomark. Prev., 5: 639-644, 1996), clonal aberrations in chromosome 8 have been reported to be in excess in smokers and in workers exposed to paints. In that study, cytogenetics was performed after therapy. In our report, we describe a population-based survey on nonlymphocytic leukemias in no...

High-grade cervical intraepithelial neoplasia (CIN2/3) represents a heterogeneous disease both with respect to clinical behavior and chromosomal aberrations detected. We hypothesized that the extent of chromosomal aberrations reflects the duration of their existence. Chromosomal profiles were determined of CIN3 of women with a known 5-year history of high-risk human papillomavirus virus (hrHPV)...

PURPOSE To develop and implement an algorithm for simulation of photorefractive surgery. It is well known that many flying-spot lasers in the market have limitations in correcting higher order aberrations, but there is little quantitative information about errors related to aberration complexity. METHODS By applying known surfaces described by Zernike polynomials of different orders it was po...

Two general types of clonal chromosome abnormality are observed in de novo acute myeloid leukemia (AML): the unbalanced aberrations with visible gain or loss of chromosome material and the balanced aberrations without such visible gain or loss. AML can be induced by therapy with cytostatic drugs and radiation. The alkylating agents reacting directly with DNA induce AML which often presents as m...