Doku kültürü teknikleri, 1900’lü yılların başında uygulanmaya başlanmış ve bu oldukça ümit verici bulunmuştur. Bitkiden alınan tek bir parçadan yeni bitkilerin çok kısa sürede, arzu edilen sayıda, dış şartlara bağımlı olmaksızın üretilebileceği fikri bilim adamlarını heyecanlandırmıştır. Ancak yapılan çalışmalarda her bitki türü için sistemin optimizasyona gerek duyması, bazı genotiplerin doku ...

In humans, a major metabolite of the atypical antipsychotic olanzapine in the plasma and in the urine was found to be an N-glucuronide. Unexpectedly, the glucuronic acid moiety was linked through a nitrogen of the benzodiazepine nucleus of olanzapine by way of a secondary amine linkage, rather than through a nitrogen on the piperazine substituent of the nucleus, to give a quaternary ammonium gl...

Fungi and plants are rich sources of thousands of secondary metabolites. The genetically coded possibilities for secondary metabolite production, the stimuli of the production, and the special phytotoxins basically determine the microscopic fungi-host plant interactions and the pathogenic lifestyle of fungi. The review introduces plant secondary metabolites usually with antifungal effect as wel...

violet is one of the ornamental plants with a good value in landscaping and herbal medicine. salicylic acid is a signaling agent involving in secondary metabolite production. the aim of this study was to evaluate the physiological responses of violet flowers to exogenous salicylic acid. this experiment was conducted in the greenhouse, as a completely randomized design. salicylic acid was spraye...

Bacterial and fungal secondary metabolism is a rich source of novel bioactive compounds with potential pharmaceutical applications as antibiotics, anti-tumor drugs or cholesterol-lowering drugs. To find new drug candidates, microbiologists are increasingly relying on sequencing genomes of a wide variety of microbes. However, rapidly and reliably pinpointing all the potential gene clusters for s...