Foreword September 27, 2013 was the 50 anniversary of Lawson Wilkins’ death. After reading the two articles by his daughter, Betsy McMaster, and his devoted protégée, Claude Migeon, we can’t help but wonder what Dr. Wilkins would have thought if he could see how we practice Pediatric Endocrinology today. Lawson Wilkins was born in 1894, and his father (also a physician) would take him along on ...

This paper looks at William Holder's "Elements of Speech" [1] from the perspective of modern phonetic and phonological literature. The structure of this presentation, first touching on general linguistic concepts, follows the three principal stages of speech production: respiration/air stream mechanism, phonation, and articulation. Holder's rendition of speech perception is discussed in conjunc...

Niklaus Wirth is one of the most influential scientists of the early computer age. His ideas and especially his programming languages have shaped generations of programmers worldwide. This paper tries to acknowledge the scientific achievements of Niklaus Wirth and to honor him as a person. A small part of the paper is also devoted to Wirth's influence on computer science at the Johannes Kepler ...

During axonogenesis, contacts made by the growth cone with its substratum are important in guiding the direction of neurone outgrowth. This study examines the contacts made by the growth cones of pioneer neurones in the embryonic grasshopper limb. Individual pioneer neurones at different stages of development were injected with horseradish peroxidase and the contacts made by the filopodia at th...

Distinct combinations of transcription factors are necessary to elicit cell fate changes in embryonic development. Yet within each group of fate-changing transcription factors, a subset called 'pioneer factors' are dominant in their ability to engage silent, unmarked chromatin and initiate the recruitment of other factors, thereby imparting new function to regulatory DNA sequences. Recent studi...