Background Hereditary spherocytosis is the most common form of inherited hemolytic anemia and is characterized by a structural defect in the RBC membrane. The disorder is commonly inherited in an autosomal dominant fashion and leads to a mild to moderate anemia. The autosomal recessive form of hereditary spherocytosis is rarely reported in association with fetal anemia and hydrops fetalis. Ca...

to AVB and myocarditis, respectively, resulting in a poor prognosis. We previously reported that fetal hydrops is associated with a poor prognosis in fetuses without CHD7 and we suggested that myocardial dysfunction, rather than the severity of bradyarrhythmia, was associated with fetal hydrops. In contrast, in fetuses with CHD, congenital bradyarrhythmia is thought to result from the structura...

The word kawaii, meaning ‘cute and sweet’ in English, has been part of the Japanese culture for centuries. While trend were historically associated with young women children, there recently an attempt to expand definition kawaii outside its traditional borders other age gender groups by creating uniquely synthesised words trends. newly coined term otona-kawaii [‘adult-cute’] refers mature who p...

Fetal tachyarrhythmia is a rare but serious disease. Without treatment, it may progress to fetal cardiac failure, hydrops fetalis and in utero fetal death. With the rapid advancement in fetal echocardiographic equipment and techniques, such arrhythmia can be diagnosed accurately during prenatal life by using M-mode echocardiogram and doppler. Prenatal control of the tachyarrhythmia can be achie...

PURPOSE To report a case of acute hydrops in pellucid marginal corneal degeneration (PMCD) documented with anterior segment optical segment tomography and successfully treated with sulphur hexafluoride (SF6) intracameral injection. METHODS A 47-year-old female patient presented with spontaneous onset of pain, redness and decreased vision in her left eye. Clinical evaluation revealed bilateral...

Electrocochleography (ECochG) has been used to assess Ménière's disease, a pathology associated with endolymphatic hydrops and low-frequency sensorineural hearing loss. However, the current ECochG techniques are limited for use at high-frequencies only (≥1 kHz) and cannot be used to assess and understand the low-frequency sensorineural hearing loss in ears with Ménière's disease. In the current...

A case of mucopolysaccharidosis type VII (MPS VII, beta glucuronidase deficiency) causing fatal hydrops fetalis in the third trimester is presented. The diagnosis was suspected on histopathological examination by the presence of foam cells in many of the viscera and foamy change in the placental Hofbauer cells. Electron microscopy showed empty cytoplasmic inclusion bodies within macrophages and...

Hydrops fetalis is rarely caused by congenital dyserythropoietic anemia (CDA). We report a patient with hydrops fetalis as a result of severe anemia. This patient needed intrauterine transfusions from 21 weeks of gestation until birth. The hematologic study showed an atypical CDA (hydrops fetalis-associated CDA) characterized by features resembling CDA type II, but negative acidified serum lysi...