Thiamazole inhibits the thyroid hormone synthesis and does not inactivate existing thyroxine triiodothyronine that circulate in blood. In this paper electrochemical behavior was monitored by cyclic voltammetry on glassy carbon (GC) electrode absence presence of sodium pertechnetate (99mTc). The influence different concentrations without radiopharmaceutical 99mTc, effect number scan cycles, 99mT...

Yttrium-90 ((90)Y)-microspheres administered via the hepatic artery has been used for the treatment of unresectable primary or metastatic cancer in the liver. Prior to (90)Y therapy, however, the (90)Y administered activity and the percent shunting to lungs must be determined, most commonly by gamma camera imaging of technetium-99m ((99m)Tc)-macroaggregated albumin (MAA). The purpose of the cur...

Cerebral amyloid angiopathy (CAA) is characterized by the deposition of amyloid aggregates in the walls of the cerebral vasculature. Recently, the development of molecular imaging probes targeting CAA has been attracting much attention. We previously reported the 99mTc-hydroxamamide (99mTc-Ham) complex with a bivalent benzothiazole scaffold as a binding moiety for amyloid aggregates ([99mTc]BT2...

Avian tuberculosis (ATBC) is a significant cause of morbidity and mortality in birds in zoos and breeding establishments. The primary sources of Mycobacterium avium subsp. avium (MAA) of serotypes 1, 2 and 3 are infected animals (esp. birds), who shed MAA in different ways and thus contaminate the environment. The first aim of this work was to compare the efficiency of the diagnostic methods th...

The molecularly imprinted polymer (MIP) based on methacrylic acid functionalized β-cyclodextrin (MAA-β-CD) monomer was synthesized for the purpose of selective recognition of benzylparaben (BzP). The MAA-β-CD monomer was produced by bridging a methacrylic acid (MAA) and β-cyclodextrin (β-CD) using toluene-2,4-diisocyanate (TDI) by reacting the -OH group of MAA and one of the primary -OH groups ...

Poly(methacrylic acid-g-ethylene glycol) (P(MAA-g-EG)) has been studied extensively in our laboratory due to its extremely promising applications in the biomedical and pharmaceutical fields. It exhibits pH-responsive interpolymer complexes that make it a promising candidate as an oral carrier for peptide and protein drug. We have developed a photoinitiated free-radical precipitation polymerizat...

The main aim was to evaluate the influence on occlusal contact area (OCA), maximum bite force (MBF), center of occlusal load (COL), and tooth pain after the nocturnal use of different mandibular advance appliances (MAAs) for snoring. Subjects were consisted of ten adult volunteers with mild snoring in Hiroshima University Hospital. Recordings of occlusal function were performed six times for tw...

Biocompatibility of intraocular lens (IOL) is critical to vision reconstruction after cataract surgery. Foldable hydrophobic acrylic IOL is vulnerable to the adhesion of extracellular matrix proteins and cells, leading to increased incidence of postoperative inflammation and capsule opacification. To increase IOL biocompatibility, we synthesized a hydrophilic copolymer P(MPC-MAA) and grafted th...

BACKGROUND Ethylene glycol monomethyl ether (EGME) exposure is associated with impaired reproductive function. The primary metabolite of EGME is methoxyacetic acid (MAA), a short-chain fatty acid that inhibits histone deacetylase activity and alters gene expression. OBJECTIVE Because estrogen signaling is necessary for normal reproductive function and modulates gene expression, the estrogen-s...